Tan Lab | DSigDB

Gene Set: D4 : CTD - sevoflurane

Collection

D4 : CTD

Chemical Name

sevoflurane ( From PubChem : SEVOFLURANE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
200.055 g/mol	0	1	2.4232	True

Structure

InChI

InChI=1S/C4H3F7O/c5-1-12-2(3(6,7)8)4(9,10)11/h2H,1H2

InChIKey

Links

Gene (18 / 36)

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Source	Type	Gene	Other
CTD	increases(cleavage)	APP	C009250
CTD	increases(reaction)	APP	C009250
CTD	affects(cleavage)	APP	C009250
CTD	decreases(reaction)	APP	C009250
CTD	increases(expression)	APP	C009250
CTD	increases(phosphorylation)	ATF2	C009250
CTD	increases(expression)	BACE1	C009250
CTD	decreases(reaction)	CALCA	C009250
CTD	increases(abundance)	CALCA	C009250
CTD	increases(cleavage)	CASP3	C009250
CTD	increases(reaction)	CASP3	C009250
CTD	decreases(reaction)	CASP3	C009250
CTD	increases(activity)	CASP3	C009250
CTD	increases(activity)	CASP3	C009250
CTD	increases(cleavage)	CASP3	C009250
CTD	increases(cleavage)	CASP3	C009250
CTD	increases(expression)	CASP3	C009250
CTD	increases(activity)	CASP7	C009250
CTD	increases(metabolic processing)	CYP2A6	C009250
CTD	increases(metabolic processing)	CYP2E1	C009250
CTD	increases(metabolic processing)	CYP3A4	C009250
CTD	decreases(reaction)	GABBR1	C009250
CTD	increases(activity)	GABBR1	C009250
CTD	affects(binding)	GABRA2	C009250
CTD	increases(activity)	GABRA2	C009250
CTD	increases(reaction)	GABRA2	C009250
CTD	affects(binding)	GABRB1	C009250
CTD	increases(activity)	GABRB1	C009250
CTD	increases(reaction)	GABRB1	C009250
CTD	increases(activity)	GLRA1	C009250
CTD	increases(reaction)	GLRA1	C009250
CTD	increases(phosphorylation)	MAP2K3	C009250
CTD	increases(phosphorylation)	MAP2K6	C009250
CTD	increases(phosphorylation)	MAP3K5	C009250
CTD	decreases(activity)	SMPD1	C009250
CTD	increases(expression)	TP53	C009250

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