Tan Lab | DSigDB

Gene Set: D4 : CTD - NSC606985

Collection

D4 : CTD

Chemical Name

NSC606985 ( From PubChem : MLS000766263 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
441.864 g/mol	2	8	3.0915	True

Structure

InChI

InChI=1S/C22H19N3O5.ClH/c1-2-22(30-18(26)9-23)15-8-17-19-13(7-12-5-3-4-6-16(12)24-19)10-25(17)20(27)14(15)11-29-21(22)28;/h3-8H,2,9-11,23H2,1H3;1H

InChIKey

DPGPIFODEPGGKB-UHFFFAOYSA-N

Links

Gene (26 / 52)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(activity)			CASP3		C514334
CTD	increases(reaction)			CASP3		C514334
CTD	increases(activity)			CASP3		C514334
CTD	increases(cleavage)			CASP3		C514334
CTD	decreases(reaction)			CASP3		C514334
CTD	decreases(expression)			CEBPA		C514334
CTD	decreases(reaction)			CEBPA		C514334
CTD	increases(degradation)			CEBPA		C514334
CTD	increases(ubiquitination)			CEBPA		C514334
CTD	decreases(expression)			HNRNPK		C514334
CTD	decreases(reaction)			HNRNPK		C514334
CTD	affects(reaction)			HNRNPK		C514334
CTD	increases(cleavage)			HNRNPK		C514334
CTD	increases(cleavage)			PARP1		C514334
CTD	increases(activity)			PRKCD		C514334
CTD	increases(cleavage)			PRKCD		C514334
CTD	increases(reaction)			PRKCD		C514334
CTD	increases(activity)			PRKCD		C514334
CTD	increases(cleavage)			PRKCD		C514334
CTD	affects(reaction)			PRKCD		C514334
CTD	decreases(expression)			PRKCD		C514334
CTD	increases(cleavage)			PRKCD		C514334
CTD	decreases(reaction)			PRKCD		C514334
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		EIF2AK3	-	GI(Protien) :
PubChem	None	uM		HCRTR1	-	GI(Protien) :
PubChem	Potency	uM	1.032	IDH1	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	None	uM		JAK2	-	GI(Protien) :
PubChem	None	uM		KLF5	-	GI(Protien) :
PubChem	None	uM		MITF	-	GI(Protien) :
PubChem	None	uM		NCOA1	-	GI(Protien) :
PubChem	None	uM		NCOA3	-	GI(Protien) :
PubChem	None	uM		NCOA3	-	GI(Protien) :
PubChem	Potency	uM	0.581	NFE2L2	-	GI(Protien) :
PubChem	EC50	uM		NOD1	-	GI(Protien) :
PubChem	IC50	uM	1.229	NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		NR5A1	-	GI(Protien) :
PubChem	None	uM		NR5A2	-	GI(Protien) :
PubChem	None	uM		NR5A2	-	GI(Protien) :
PubChem	None	uM		S1PR4	-	GI(Protien) :
PubChem	None	uM		S1PR4	-	GI(Protien) :
PubChem	IC50	uM		SAE1	-	GI(Protien) :
PubChem	Potency	uM	1.158	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	2.239	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	2.311	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.065	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.164	TDP1	-	GI(Protien) :
PubChem	IC50	uM		UBA2	-	GI(Protien) :
PubChem	IC50	uM		UBE2I	-	GI(Protien) :

Download gene sets

gmt, text, Detailed text