Tan Lab | DSigDB

Gene Set: D4 : CTD - abexinostat

Collection

D4 : CTD

Chemical Name

abexinostat ( From PubChem : PCI-24781 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
397.424 g/mol	3	8	3.204	True

Structure

InChI

InChI=1S/C21H23N3O5/c1-24(2)13-17-16-5-3-4-6-18(16)29-19(17)21(26)22-11-12-28-15-9-7-14(8-10-15)20(25)23-27/h3-10,27H,11-13H2,1-2H3,(H,22,26)(H,23,25)

InChIKey

MAUCONCHVWBMHK-UHFFFAOYSA-N

Links

Gene (15 / 27)

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Source	Type	Gene	Other
CTD	affects(cotreatment)	CASP3	C512352
CTD	increases(activity)	CASP3	C512352
CTD	increases(cleavage)	CASP8	C512352
CTD	increases(reaction)	CASP8	C512352
CTD	increases(cleavage)	CASP9	C512352
CTD	increases(reaction)	CASP9	C512352
CTD	decreases(expression)	CCL3	C512352
CTD	decreases(expression)	CCL7	C512352
CTD	increases(expression)	CDKN1A	C512352
CTD	increases(reaction)	CDKN1A	C512352
CTD	increases(expression)	HMOX1	C512352
CTD	increases(reaction)	HMOX1	C512352
CTD	decreases(expression)	HMOX2	C512352
CTD	increases(reaction)	HMOX2	C512352
CTD	decreases(expression)	IKBKB	C512352
CTD	increases(reaction)	IKBKB	C512352
CTD	decreases(expression)	MYC	C512352
CTD	affects(cotreatment)	MYC	C512352
CTD	increases(reaction)	MYC	C512352
CTD	decreases(expression)	NFKB1	C512352
CTD	affects(cotreatment)	PARP1	C512352
CTD	increases(activity)	PARP1	C512352
CTD	decreases(expression)	RELB	C512352
CTD	decreases(expression)	TXN2	C512352
CTD	increases(reaction)	TXN2	C512352
CTD	decreases(expression)	TXNRD2	C512352
CTD	increases(reaction)	TXNRD2	C512352

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