Tan Lab | DSigDB

Gene Set: D4 : CTD - PD168393

Collection

D4 : CTD

Chemical Name

PD168393 ( From PubChem : PD 168393 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
369.215 g/mol	2	4	4.4064	True

Structure

InChI

InChI=1S/C17H13BrN4O/c1-2-16(23)21-13-6-7-15-14(9-13)17(20-10-19-15)22-12-5-3-4-11(18)8-12/h2-10H,1H2,(H,21,23)(H,19,20,22)

InChIKey

HTUBKQUPEREOGA-UHFFFAOYSA-N

Links

Gene (15 / 47)

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Source	Type	Unit	Gene	PMID	Other
CTD	affects(cotreatment)		BAD		C509204
CTD	increases(expression)		BAD		C509204
CTD	affects(cotreatment)		CASP3		C509204
CTD	increases(activity)		CASP3		C509204
CTD	increases(cleavage)		CASP3		C509204
CTD	increases(expression)		CCL2		C509204
CTD	increases(secretion)		CCL2		C509204
CTD	decreases(reaction)		CCL2		C509204
CTD	affects(cotreatment)		CDKN1A		C509204
CTD	increases(expression)		CDKN1A		C509204
CTD	decreases(reaction)		CXCL10		C509204
CTD	increases(secretion)		CXCL10		C509204
CTD	increases(expression)		CXCL10		C509204
CTD	decreases(reaction)		CXCL8		C509204
CTD	increases(expression)		CXCL8		C509204
CTD	affects(cotreatment)		CYCS		C509204
CTD	affects(localization)		CYCS		C509204
CTD	affects(localization)		EGFR		C509204
CTD	affects(cotreatment)		EGFR		C509204
CTD	decreases(phosphorylation)		EGFR		C509204
CTD	decreases(reaction)		EGFR		C509204
CTD	increases(phosphorylation)		EGFR		C509204
CTD	decreases(reaction)		EGFR		C509204
CTD	decreases(phosphorylation)		EGFR		C509204
CTD	decreases(reaction)		JAK3		C509204
CTD	increases(phosphorylation)		JAK3		C509204
CTD	affects(cotreatment)		MAPK1		C509204
CTD	decreases(activity)		MAPK1		C509204
CTD	decreases(phosphorylation)		MAPK1		C509204
CTD	decreases(reaction)		MAPK1		C509204
CTD	increases(phosphorylation)		MAPK1		C509204
CTD	affects(cotreatment)		MAPK3		C509204
CTD	decreases(activity)		MAPK3		C509204
CTD	decreases(phosphorylation)		MAPK3		C509204
CTD	decreases(reaction)		MAPK3		C509204
CTD	increases(phosphorylation)		MAPK3		C509204
CTD	decreases(reaction)		MAPK8		C509204
CTD	increases(phosphorylation)		MAPK8		C509204
CTD	affects(localization)		TGFA		C509204
CTD	decreases(reaction)		TGFA		C509204
CTD	affects(cotreatment)		TP53		C509204
CTD	increases(expression)		TP53		C509204
ChEMBL	Activity	-	BMX	-	Target : CHEMBL3834
ChEMBL	Activity	-	BMX	-	Target : CHEMBL3834
ChEMBL	Inhibition	-	EGFR	-	Target : CHEMBL203
ChEMBL	Inhibition	-	EGFR	-	Target : CHEMBL203
ChEMBL	Inhibition	-	EGFR	-	Target : CHEMBL203

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