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Gene Set: D4 : CTD - necrostatin-1

Collection D4 : CTD
Chemical Name necrostatin-1 ( From PubChem : NECROSTATIN-1 )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
259.327 g/mol 2 4 1.6922 True
Structure
InChI InChI=1S/C13H13N3OS/c1-16-12(17)11(15-13(16)18)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,14H,6H2,1H3,(H,15,18)/t11-/m0/s1
InChIKey TXUWMXQFNYDOEZ-NSHDSACASA-N
Links

Gene (6 / 11)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDaffects(cotreatment)BID
C507699
CTDincreases(expression)BID
C507699
CTDaffects(cotreatment)CASP3
C507699
CTDincreases(activity)CASP3
C507699
CTDincreases(cleavage)CASP3
C507699
CTDaffects(cotreatment)PMAIP1
C507699
CTDincreases(expression)PMAIP1
C507699
PubChem PotencyuM6.310CYP3A4-GI(Protien) :
PubChem PotencyuM12.589SMN2-GI(Protien) :
ChEMBLPotencynM6309.600CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM12589.300SMN1; SMN2
-Target : CHEMBL1293232
Download gene sets gmt, text, Detailed text
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