DSigDB Home
Search Gene
Collections
Browse Gene Sets
Download
Help

Gene Set: D4 : CTD - 2,5-dimethylcelecoxib

Collection D4 : CTD
Chemical Name 2,5-dimethylcelecoxib ( From PubChem : 2,5-DIMETHYLCELECOXIB )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
395.399 g/mol 1 5 5.6034 False(3/4)
Structure
InChI InChI=1S/C18H16F3N3O2S/c1-11-3-4-12(2)15(9-11)16-10-17(18(19,20)21)23-24(16)13-5-7-14(8-6-13)27(22,25)26/h3-10H,1-2H3,(H2,22,25,26)
InChIKey NTFOSUUWGCDXEF-UHFFFAOYSA-N
Links

Gene (9 / 16)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDdecreases(expression)BIRC5
C506698
CTDincreases(activity)CASP3
C506698
CTDincreases(cleavage)CASP3
C506698
CTDincreases(activity)CASP7
C506698
CTDincreases(expression)DDIT3
C506698
CTDdecreases(reaction)IL6
C506698
CTDincreases(phosphorylation)IL6
C506698
CTDdecreases(reaction)MAP2K1
C506698
CTDincreases(phosphorylation)MAP2K1
C506698
CTDdecreases(phosphorylation)MAP2K1
C506698
CTDdecreases(reaction)MAP2K2
C506698
CTDincreases(phosphorylation)MAP2K2
C506698
CTDdecreases(phosphorylation)MAP2K2
C506698
CTDincreases(cleavage)PARP1
C506698
CTDdecreases(reaction)STAT3
C506698
CTDincreases(phosphorylation)STAT3
C506698
Download gene sets gmt, text, Detailed text
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).