Tan Lab | DSigDB

Gene Set: D4 : CTD - Dichlorvos

Collection

D4 : CTD

Chemical Name

Dichlorvos ( From PubChem : DICHLORVOS )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
220.976 g/mol	0	4	2.6804	True

Structure

InChI

InChI=1S/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3

InChIKey

OEBRKCOSUFCWJD-UHFFFAOYSA-N

Links

Gene (29 / 70)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			ACHE		D004006
CTD	decreases(reaction)			ACHE		D004006
CTD	affects(cotreatment)			ACHE		D004006
CTD	decreases(activity)			ACHE		D004006
CTD	increases(reaction)			ACHE		D004006
CTD	decreases(activity)			ACHE		D004006
CTD	increases(phosphorylation)			ACHE		D004006
CTD	affects(binding)			ACHE		D004006
CTD	decreases(reaction)			ACHE		D004006
CTD	decreases(activity)			ACHE		D004006
CTD	decreases(reaction)			ACHE		D004006
CTD	decreases(activity)			ACHE		D004006
CTD	decreases(reaction)			ACHE		D004006
CTD	affects(binding)			ALB		D004006
CTD	decreases(activity)			APEH		D004006
CTD	increases(secretion)			APP		D004006
CTD	increases(activity)			AR		D004006
CTD	increases(reaction)			AR		D004006
CTD	decreases(expression)			AR		C498475
CTD	affects(binding)			BCHE		D004006
CTD	decreases(activity)			BCHE		D004006
CTD	decreases(activity)			BCHE		D004006
CTD	decreases(activity)			BCHE		D004006
CTD	increases(response to substance)			BCHE		D004006
CTD	decreases(activity)			BCHE		D004006
CTD	decreases(reaction)			BCHE		D004006
CTD	decreases(activity)			BCHE		D004006
CTD	decreases(reaction)			BCHE		D004006
CTD	decreases(reaction)			CASP3		D004006
CTD	increases(activity)			CASP3		D004006
CTD	decreases(expression)			CCND1		C498475
CTD	decreases(expression)			CCNE1		C498475
CTD	decreases(expression)			CDKN1B		C498475
CTD	increases(expression)			CDKN1B		C498475
CTD	affects(activity)			CHRNA4		D004006
CTD	affects(binding)			CHRNA4		D004006
CTD	decreases(reaction)			CHRNA4		D004006
CTD	affects(activity)			CHRNB2		D004006
CTD	affects(binding)			CHRNB2		D004006
CTD	decreases(reaction)			CHRNB2		D004006
CTD	decreases(activity)			ESR1		D004006
CTD	decreases(expression)			GNLY		D004006
CTD	decreases(expression)			GZMA		D004006
CTD	decreases(expression)			GZMB		D004006
CTD	decreases(expression)			GZMK		D004006
CTD	decreases(expression)			KLK3		C498475
CTD	decreases(reaction)			LCAT		D004006
CTD	increases(chemical synthesis)			LCAT		D004006
CTD	increases(metabolic processing)			LCAT		D004006
CTD	decreases(activity)			LCAT		D004006
CTD	increases(activity)			NFE2L2		D004006
CTD	decreases(activity)			PNPLA6		D004006
CTD	decreases(expression)			PRF1		D004006
CTD	decreases(phosphorylation)			RB1		C498475
CTD	affects(binding)			TF		D004006
PubChem	Ratio Potency (uM)	uM	15.089	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	15.089	AR	-	GI(Protien) :
PubChem	Potency	uM	21.132	CXCL8	-	GI(Protien) :
PubChem	Potency	uM	66.824	CXCL8	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	10.682	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	13.974	ESR1	-	GI(Protien) :
PubChem	Potency	uM	11.886	GMNN	-	GI(Protien) :
PubChem	Potency	uM	13.336	GMNN	-	GI(Protien) :
PubChem	Potency	uM	30.638	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	36.784	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	37.578	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	42.163	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	39.811	NR1I2	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :
PubChem	Potency	uM	11.886	TDP1	-	GI(Protien) :

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