Tan Lab | DSigDB

Gene Set: D4 : CTD - 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione

Collection

D4 : CTD

Chemical Name

4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ( From PubChem : TDZD-8 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
222.264 g/mol	0	5	0.6568	True

Structure

InChI

InChI=1S/C10H10N2O2S/c1-11-9(13)12(10(14)15-11)7-8-5-3-2-4-6-8/h2-6H,7H2,1H3

InChIKey

Links

Gene (21 / 27)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(phosphorylation)			AKT1		C494356
CTD	decreases(expression)			BCL2		C494356
CTD	decreases(reaction)			BCL2		C494356
CTD	decreases(expression)			CCNA2		C494356
CTD	decreases(expression)			CCND2		C494356
CTD	decreases(reaction)			CCND2		C494356
CTD	decreases(expression)			CCNE2		C494356
CTD	decreases(expression)			CDC25C		C494356
CTD	decreases(expression)			CDC6		C494356
CTD	increases(expression)			CDKN1A		C494356
CTD	increases(phosphorylation)			CREB1		C494356
CTD	decreases(activity)			GSK3B		C494356
CTD	decreases(reaction)			LGALS3		C494356
CTD	increases(expression)			LGALS3		C494356
CTD	increases(phosphorylation)			MAPK1		C494356
CTD	increases(phosphorylation)			MAPK3		C494356
CTD	increases(phosphorylation)			MAPK8		C494356
CTD	increases(phosphorylation)			MAPK9		C494356
CTD	decreases(reaction)			MIR302B		C494356
CTD	increases(expression)			MIR302B		C494356
CTD	decreases(reaction)			MIR497		C494356
CTD	increases(expression)			MIR497		C494356
CTD	increases(phosphorylation)			NFKBIA		C494356
CTD	increases(phosphorylation)			TP53		C494356
PubChem	Potency	uM	19.953	KAT2A	-	GI(Protien) :
PubChem	Potency	uM	5.012	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	19952.600	KAT2A	-	Target : CHEMBL5501

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