Tan Lab | DSigDB

Gene Set: D4 : CTD - icilin

Collection

D4 : CTD

Chemical Name

icilin ( From PubChem : ICILIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
311.292 g/mol	2	4	3.7881	True

Structure

InChI

InChI=1S/C16H13N3O4/c20-15-7-2-1-6-14(15)18-9-8-13(17-16(18)21)11-4-3-5-12(10-11)19(22)23/h1-8,10,20H,9H2,(H,17,21)

InChIKey

Links

Gene (4 / 17)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(reaction)			TRPM8		C490483
CTD	increases(transport)			TRPM8		C490483
CTD	increases(activity)			TRPM8		C490483
CTD	increases(activity)			TRPM8		C490483
CTD	increases(transport)			TRPM8		C490483
PubChem	Potency	uM	6.310	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	1.000	CYP2C9	-	GI(Protien) :
PubChem	None	uM		CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	18.888	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	50.119	EHMT2	-	GI(Protien) :
ChEMBL	Potency	nM	6309.600	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	6309.570	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	1000.000	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	1000.000	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	50118.700	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	18887.600	EHMT2	-	Target : CHEMBL6032

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