Tan Lab | DSigDB

Gene Set: D4 : CTD - belinostat

Collection

D4 : CTD

Chemical Name

belinostat ( From PubChem : BELINOSTAT )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
318.348 g/mol	3	6	3.5507	True

Structure

InChI

InChI=1S/C15H14N2O4S/c18-15(16-19)10-9-12-5-4-8-14(11-12)22(20,21)17-13-6-2-1-3-7-13/h1-11,17,19H,(H,16,18)/b10-9+

InChIKey

NCNRHFGMJRPRSK-MDZDMXLPSA-N

Links

Gene (64 / 84)

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Source	Type	Gene	Other
CTD	decreases(expression)	ABL1	C487081
CTD	increases(phosphorylation)	AKT1	C487081
CTD	decreases(activity)	AURKA	C487081
CTD	decreases(expression)	AURKA	C487081
CTD	decreases(activity)	AURKB	C487081
CTD	decreases(expression)	AURKB	C487081
CTD	increases(expression)	BCL2L11	C487081
CTD	decreases(expression)	BCLAF1	C487081
CTD	decreases(expression)	BIRC5	C487081
CTD	decreases(expression)	CAD	C487081
CTD	increases(cleavage)	CASP3	C487081
CTD	increases(reaction)	CASP3	C487081
CTD	increases(cleavage)	CASP9	C487081
CTD	increases(reaction)	CASP9	C487081
CTD	decreases(expression)	CCNA2	C487081
CTD	decreases(expression)	CCNB1	C487081
CTD	decreases(expression)	CDC25B	C487081
CTD	decreases(expression)	CDK1	C487081
CTD	decreases(expression)	CDK4	C487081
CTD	increases(expression)	CDKN1A	C487081
CTD	increases(reaction)	CDKN1A	C487081
CTD	increases(expression)	CDKN1A	C487081
CTD	decreases(expression)	CDKN2A	C487081
CTD	increases(expression)	CLU	C487081
CTD	increases(reaction)	CLU	C487081
CTD	increases(expression)	CLU	C487081
CTD	increases(expression)	CTGF	C487081
CTD	decreases(expression)	CTPS1	C487081
CTD	increases(expression)	CXCL8	C487081
CTD	increases(expression)	CYR61	C487081
CTD	decreases(expression)	DDX21	C487081
CTD	increases(expression)	DHRS2	C487081
CTD	increases(expression)	DNAJB1	C487081
CTD	decreases(expression)	EIF4G2	C487081
CTD	increases(phosphorylation)	GSK3B	C487081
CTD	increases(expression)	H1F0	C487081
CTD	increases(expression)	H1FX	C487081
CTD	increases(expression)	IFNGR1	C487081
CTD	increases(expression)	IGF1	C487081
CTD	increases(expression)	IL6	C487081
CTD	decreases(expression)	INCENP	C487081
CTD	decreases(expression)	KEAP1	C487081
CTD	decreases(expression)	KPNB1	C487081
CTD	increases(expression)	MAGEA1	C487081
CTD	increases(reaction)	MAGEA1	C487081
CTD	increases(expression)	MAP1LC3B	C487081
CTD	decreases(expression)	MCM3	C487081
CTD	decreases(expression)	MCM7	C487081
CTD	increases(expression)	MLH1	C487081
CTD	increases(reaction)	MLH1	C487081
CTD	increases(expression)	NFKB1	C487081
CTD	decreases(reaction)	NFKB1	C487081
CTD	increases(expression)	NFKBIA	C487081
CTD	decreases(reaction)	NFKBIA	C487081
CTD	increases(expression)	ODC1	C487081
CTD	decreases(expression)	PA2G4	C487081
CTD	increases(cleavage)	PARP1	C487081
CTD	increases(reaction)	PARP1	C487081
CTD	increases(expression)	PEG10	C487081
CTD	decreases(expression)	RAC1	C487081
CTD	decreases(expression)	RAN	C487081
CTD	decreases(expression)	RCC2	C487081
CTD	increases(acetylation)	RELA	C487081
CTD	decreases(reaction)	RELA	C487081
CTD	increases(expression)	SAT1	C487081
CTD	increases(expression)	TACC1	C487081
CTD	increases(expression)	TGFB2	C487081
CTD	decreases(expression)	TP53	C487081
CTD	decreases(expression)	TPX2	C487081
CTD	increases(expression)	TUFT1	C487081
CTD	increases(expression)	TWIST1	C487081
CTD	decreases(expression)	TYMS	C487081
CTD	decreases(glucuronidation)	UGT1A1	C487081
CTD	increases(glucuronidation)	UGT1A1	C487081
CTD	increases(expression)	VIM	C487081
CTD	decreases(reaction)	VIM	C487081
CTD	increases(expression)	WNT3A	C487081
CTD	increases(expression)	WNT4	C487081
CTD	decreases(degradation)	WWTR1	C487081
CTD	increases(expression)	WWTR1	C487081
CTD	increases(stability)	WWTR1	C487081
CTD	decreases(reaction)	WWTR1	C487081
CTD	decreases(expression)	YAP1	C487081
CTD	decreases(phosphorylation)	YAP1	C487081

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