Tan Lab | DSigDB

Gene Set: D4 : CTD - nobiletin

Collection

D4 : CTD

Chemical Name

nobiletin ( From PubChem : NOBILETIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
402.395 g/mol	0	8	3.5116	True

Structure

InChI

InChI=1S/C21H22O8/c1-23-13-8-7-11(9-15(13)24-2)14-10-12(22)16-17(25-3)19(26-4)21(28-6)20(27-5)18(16)29-14/h7-10H,1-6H3

InChIKey

Links

Gene (21 / 29)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ASNS		C008661
CTD	decreases(expression)			CCNA2		C008661
CTD	decreases(expression)			CCNE2		C008661
CTD	decreases(expression)			CD74		C008661
CTD	increases(metabolic processing)			CYP1A1		C008661
CTD	decreases(reaction)			CYP1A1		C008661
CTD	increases(expression)			CYP1A1		C008661
CTD	increases(expression)			CYP1A1		C008661
CTD	increases(metabolic processing)			CYP1A2		C008661
CTD	increases(expression)			CYP1B1		C008661
CTD	increases(expression)			DDIT3		C008661
CTD	decreases(expression)			DEPDC1		C008661
CTD	decreases(expression)			E2F8		C008661
CTD	decreases(expression)			HIST1H1B		C008661
CTD	decreases(expression)			KIF11		C008661
CTD	decreases(expression)			MMP7		C008661
CTD	increases(expression)			SLC6A9		C008661
CTD	increases(expression)			TMEM116		C008661
CTD	increases(expression)			TRIB3		C008661
CTD	decreases(expression)			TXNIP		C008661
PubChem	Potency	uM	25.119	CYP3A4	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		MAP3K3	-	GI(Protien) :
PubChem	Potency	uM	10.322	TDP1	-	GI(Protien) :
PubChem	Potency	uM	20.596	TDP1	-	GI(Protien) :
PubChem	Potency	uM	20.596	TDP1	-	GI(Protien) :
PubChem	Potency	uM	23.109	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	25118.900	CYP3A4	-	Target : CHEMBL340

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