Tan Lab | DSigDB

Gene Set: D4 : CTD - 4-nitrosodimethylaniline

Collection

D4 : CTD

Chemical Name

4-nitrosodimethylaniline ( From PubChem : N,N-DIMETHYL-4-NITROSOANILINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
150.178 g/mol	0	3	2.1505	True

Structure

InChI

InChI=1S/C8H10N2O/c1-10(2)8-5-3-7(9-11)4-6-8/h3-6H,1-2H3

InChIKey

Links

Gene (13 / 26)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			MGMT		C008651
PubChem	Potency-Replicate_1	uM	21.690	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.756	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	27.389	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	33.082	AHR	-	GI(Protien) :
PubChem	Potency	uM	70.795	AHR	-	GI(Protien) :
PubChem	Potency	uM	0.398	ALDH1A1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	3.369	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	15.355	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	15.402	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	24.541	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	9.718	CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.690	CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	12.197	ESR1	-	GI(Protien) :
PubChem	Potency	uM	22.387	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	6.551	HSPB1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	24.541	HSPB1	-	GI(Protien) :
PubChem	Potency	uM	13.333	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	26.603	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	27.389	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	38.895	NR3C1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.872	PPARD	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM		PPARG	-	GI(Protien) :
PubChem	Potency	uM	5.012	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.562	TDP1	-	GI(Protien) :
PubChem	Potency	uM	5.012	TDP1	-	GI(Protien) :

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