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Gene Set: D4 : CTD - CP-654577

Collection D4 : CTD
Chemical Name CP-654577 ( From PubChem : UNII-W39547M0FP )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
544.643 g/mol 2 6 6.5223 False(2/4)
Structure
InChI InChI=1S/C34H32N4O3/c1-40-33-16-25(12-14-32(33)41-26-5-3-2-4-6-26)37-34-27-15-24(11-13-31(27)35-21-36-34)23-9-7-22(8-10-23)17-38-18-28-29(19-38)30(28)20-39/h2-16,21,28-30,39H,17-20H2,1H3,(H,35,36,37)/t28-,29+,30+
InChIKey WZZXMNBOPNKKSX-BKHFGAQXSA-N
Links

Gene (10 / 12)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDdecreases(activity)AKT1
C477330
CTDdecreases(phosphorylation)AKT1
C477330
CTDdecreases(expression)CCND2
C477330
CTDdecreases(expression)CCND3
C477330
CTDdecreases(expression)CCNE1
C477330
CTDincreases(expression)CDKN1B
C477330
CTDdecreases(activity)ERBB2
C477330
CTDdecreases(phosphorylation)ERBB2
C477330
CTDdecreases(phosphorylation)MAPK1
C477330
CTDdecreases(expression)MAPK14
C477330
CTDdecreases(phosphorylation)MAPK3
C477330
CTDdecreases(phosphorylation)RB1
C477330
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Aurora, CO 80045, USA

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