Tan Lab | DSigDB

Gene Set: D4 : CTD - pomiferin

Collection

D4 : CTD

Chemical Name

pomiferin ( From PubChem : POMIFERIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
420.454 g/mol	3	6	5.2697	False(3/4)

Structure

InChI

InChI=1S/C25H24O6/c1-13(2)5-7-15-21(28)20-22(29)17(14-6-8-18(26)19(27)11-14)12-30-24(20)16-9-10-25(3,4)31-23(15)16/h5-6,8-12,26-28H,7H2,1-4H3

InChIKey

GHCZYXUOYFOXIP-UHFFFAOYSA-N

Links

Gene (46 / 60)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ACLY		C474837
CTD	increases(expression)			AQP1		C474837
CTD	increases(expression)			AQP3		C474837
CTD	decreases(expression)			AR		C474837
CTD	increases(expression)			CD44		C474837
CTD	increases(expression)			CDH1		C474837
CTD	increases(expression)			COL1A1		C474837
CTD	increases(expression)			COX1		C474837
CTD	decreases(expression)			CYGB		C474837
CTD	decreases(expression)			EGF		C474837
CTD	decreases(expression)			ESR2		C474837
CTD	decreases(expression)			FBN1		C474837
CTD	increases(expression)			FGF1		C474837
CTD	increases(expression)			GRN		C474837
CTD	increases(expression)			HSPB1		C474837
CTD	decreases(expression)			IGF1		C474837
CTD	decreases(expression)			KL		C474837
CTD	increases(expression)			KRT5		C474837
CTD	decreases(expression)			MC1R		C474837
CTD	increases(expression)			NOS3		C474837
CTD	decreases(expression)			PGR		C474837
CTD	increases(expression)			PLOD3		C474837
CTD	decreases(expression)			POMC		C474837
CTD	decreases(expression)			PPARG		C474837
CTD	decreases(expression)			PTGER1		C474837
CTD	decreases(expression)			RAD23A		C474837
CTD	increases(expression)			RARA		C474837
CTD	decreases(expression)			SOD3		C474837
CTD	decreases(expression)			SRD5A2		C474837
CTD	decreases(expression)			TERT		C474837
CTD	increases(expression)			TPT1		C474837
CTD	increases(expression)			TXN		C474837
CTD	decreases(expression)			TYRP1		C474837
PubChem	None	uM		ADAM17	-	GI(Protien) :
PubChem	Potency	uM	3.981	ALOX15	-	GI(Protien) :
PubChem	Potency	uM	1.995	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	3.162	CYP2C9	-	GI(Protien) :
PubChem	None	uM		CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	9.200	GMNN	-	GI(Protien) :
PubChem	AC50_uM	uM	13.340	HSP90AA1	-	GI(Protien) :
PubChem	Potency	uM	44.668	IDH1	-	GI(Protien) :
PubChem	Potency	uM	52.119	IDH1	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	Potency	uM	25.119	MAPT	-	GI(Protien) :
PubChem	None	uM		MAPT	-	GI(Protien) :
PubChem	None	uM		PTGER2	-	GI(Protien) :
PubChem	Potency	uM	10.000	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.581	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.731	TDP1	-	GI(Protien) :
PubChem	Potency	uM	1.300	TDP1	-	GI(Protien) :
PubChem	Potency	uM	1.458	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	3981.100	ALOX15	-	Target : CHEMBL2903
ChEMBL	AC50	nM	1995.260	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	1995.300	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	3162.280	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	3162.300	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	22387.200	KDM4A	-	Target : CHEMBL5896
ChEMBL	Potency	nM	3548.100	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	25118.900	MAPT	-	Target : CHEMBL1293224

Download gene sets

gmt, text, Detailed text