Tan Lab | DSigDB

Gene Set: D4 : CTD - sorafenib

Collection

D4 : CTD

Chemical Name

sorafenib ( From PubChem : SORAFENIB )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Approved	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
464.825 g/mol	3	7	6.0866	False(3/4)

Structure

InChI

InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)

InChIKey

MLDQJTXFUGDVEO-UHFFFAOYSA-N

Links

Gene (113 / 536)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			ABCB11		C471405
CTD	affects(response to substance)			ABCC1		C471405
CTD	affects(response to substance)			ABCC2		C471405
CTD	affects(response to substance)			ABCC3		C471405
CTD	affects(cotreatment)			ABL1		C471405
CTD	decreases(reaction)			ABL1		C471405
CTD	increases(phosphorylation)			ABL1		C471405
CTD	decreases(activity)			ABL1		C471405
CTD	decreases(phosphorylation)			ABL1		C471405
CTD	affects(localization)			AIFM1		C471405
CTD	decreases(reaction)			AIFM1		C471405
CTD	affects(localization)			AIFM1		C471405
CTD	affects(cotreatment)			AIFM1		C471405
CTD	affects(localization)			AIFM1		C471405
CTD	affects(cotreatment)			AIFM1		C471405
CTD	affects(cotreatment)			AIFM1		C471405
CTD	affects(localization)			AIFM1		C471405
CTD	affects(cotreatment)			AIFM1		C471405
CTD	affects(localization)			AIFM1		C471405
CTD	decreases(phosphorylation)			AKT1		C471405
CTD	increases(reaction)			AKT1		C471405
CTD	affects(cotreatment)			AKT1		C471405
CTD	decreases(reaction)			AKT1		C471405
CTD	increases(cleavage)			AKT1		C471405
CTD	decreases(response to substance)			AKT1		C471405
CTD	decreases(phosphorylation)			AKT1		C471405
CTD	affects(reaction)			AKT1		C471405
CTD	increases(expression)			ATF4		C471405
CTD	increases(reaction)			ATF4		C471405
CTD	decreases(activity)			ATF4		C471405
CTD	decreases(expression)			ATF4		C471405
CTD	affects(cotreatment)			ATG5		C471405
CTD	decreases(reaction)			ATG5		C471405
CTD	increases(cleavage)			ATG5		C471405
CTD	affects(binding)			ATG5		C471405
CTD	increases(reaction)			ATG5		C471405
CTD	increases(expression)			ATG5		C471405
CTD	decreases(expression)			ATG5		C471405
CTD	decreases(phosphorylation)			BAD		C471405
CTD	increases(expression)			BAD		C471405
CTD	increases(activity)			BAK1		C471405
CTD	affects(cotreatment)			BAK1		C471405
CTD	affects(folding)			BAK1		C471405
CTD	decreases(reaction)			BAK1		C471405
CTD	increases(activity)			BAK1		C471405
CTD	increases(expression)			BAK1		C471405
CTD	increases(reaction)			BAK1		C471405
CTD	decreases(expression)			BAK1		C471405
CTD	increases(expression)			BAK1		C471405
CTD	affects(folding)			BAX		C471405
CTD	decreases(reaction)			BAX		C471405
CTD	increases(activity)			BAX		C471405
CTD	affects(cotreatment)			BAX		C471405
CTD	affects(folding)			BAX		C471405
CTD	decreases(reaction)			BAX		C471405
CTD	increases(activity)			BAX		C471405
CTD	affects(localization)			BAX		C471405
CTD	increases(activity)			BAX		C471405
CTD	increases(cleavage)			BAX		C471405
CTD	increases(expression)			BAX		C471405
CTD	affects(cotreatment)			BCL2		C471405
CTD	decreases(expression)			BCL2		C471405
CTD	affects(cotreatment)			BCL2		C471405
CTD	decreases(expression)			BCL2		C471405
CTD	decreases(reaction)			BCL2		C471405
CTD	increases(expression)			BCL2		C471405
CTD	decreases(expression)			BCL2		C471405
CTD	increases(reaction)			BCL2		C471405
CTD	decreases(expression)			BCL2		C471405
CTD	increases(cleavage)			BCL2		C471405
CTD	affects(folding)			BCL2L1		C471405
CTD	decreases(reaction)			BCL2L1		C471405
CTD	increases(activity)			BCL2L1		C471405
CTD	increases(cleavage)			BCL2L1		C471405
CTD	affects(cotreatment)			BCL2L1		C471405
CTD	decreases(expression)			BCL2L1		C471405
CTD	decreases(expression)			BCL2L1		C471405
CTD	increases(reaction)			BCL2L1		C471405
CTD	decreases(expression)			BCL2L1		C471405
CTD	affects(localization)			BCL2L11		C471405
CTD	affects(cotreatment)			BCL2L11		C471405
CTD	increases(expression)			BCL2L11		C471405
CTD	decreases(expression)			BCL2L11		C471405
CTD	increases(expression)			BCL2L11		C471405
CTD	affects(cotreatment)			BCR		C471405
CTD	decreases(reaction)			BCR		C471405
CTD	increases(phosphorylation)			BCR		C471405
CTD	decreases(activity)			BCR		C471405
CTD	decreases(phosphorylation)			BCR		C471405
CTD	affects(cotreatment)			BID		C471405
CTD	increases(cleavage)			BID		C471405
CTD	increases(reaction)			BID		C471405
CTD	affects(cotreatment)			BID		C471405
CTD	increases(cleavage)			BID		C471405
CTD	decreases(expression)			BIRC3		C471405
CTD	decreases(expression)			BIRC5		C471405
CTD	decreases(reaction)			BIRC5		C471405
CTD	increases(expression)			BIRC5		C471405
CTD	decreases(expression)			BIRC5		C471405
CTD	decreases(activity)			BIRC5		C471405
CTD	decreases(expression)			BIRC5		C471405
CTD	decreases(reaction)			BRAF		C471405
CTD	increases(phosphorylation)			BRAF		C471405
CTD	decreases(activity)			BRAF		C471405
CTD	decreases(activity)			BRAF		C471405
CTD	affects(cotreatment)			CASP3		C471405
CTD	decreases(reaction)			CASP3		C471405
CTD	increases(cleavage)			CASP3		C471405
CTD	decreases(reaction)			CASP3		C471405
CTD	increases(activity)			CASP3		C471405
CTD	increases(cleavage)			CASP3		C471405
CTD	decreases(reaction)			CASP3		C471405
CTD	increases(activity)			CASP3		C471405
CTD	increases(cleavage)			CASP3		C471405
CTD	affects(cleavage)			CASP3		C471405
CTD	affects(cotreatment)			CASP3		C471405
CTD	increases(cleavage)			CASP3		C471405
CTD	affects(cotreatment)			CASP3		C471405
CTD	increases(cleavage)			CASP3		C471405
CTD	affects(cotreatment)			CASP3		C471405
CTD	increases(activity)			CASP3		C471405
CTD	increases(cleavage)			CASP3		C471405
CTD	affects(cotreatment)			CASP3		C471405
CTD	increases(cleavage)			CASP3		C471405
CTD	affects(cotreatment)			CASP3		C471405
CTD	increases(cleavage)			CASP3		C471405
CTD	affects(cotreatment)			CASP3		C471405
CTD	increases(cleavage)			CASP3		C471405
CTD	decreases(reaction)			CASP3		C471405
CTD	increases(activity)			CASP3		C471405
CTD	increases(activity)			CASP3		C471405
CTD	increases(activity)			CASP3		C471405
CTD	increases(cleavage)			CASP3		C471405
CTD	increases(cleavage)			CASP3		C471405
CTD	affects(cotreatment)			CASP7		C471405
CTD	increases(activity)			CASP7		C471405
CTD	increases(cleavage)			CASP7		C471405
CTD	increases(activity)			CASP7		C471405
CTD	increases(activity)			CASP7		C471405
CTD	increases(cleavage)			CASP7		C471405
CTD	affects(cotreatment)			CASP8		C471405
CTD	decreases(reaction)			CASP8		C471405
CTD	increases(cleavage)			CASP8		C471405
CTD	decreases(reaction)			CASP8		C471405
CTD	increases(activity)			CASP8		C471405
CTD	increases(cleavage)			CASP8		C471405
CTD	affects(binding)			CASP8		C471405
CTD	increases(reaction)			CASP8		C471405
CTD	affects(localization)			CASP8		C471405
CTD	affects(cotreatment)			CASP8		C471405
CTD	increases(cleavage)			CASP8		C471405
CTD	increases(reaction)			CASP8		C471405
CTD	increases(activity)			CASP8		C471405
CTD	affects(cotreatment)			CASP8		C471405
CTD	increases(cleavage)			CASP8		C471405
CTD	affects(cotreatment)			CASP8		C471405
CTD	increases(cleavage)			CASP8		C471405
CTD	affects(cotreatment)			CASP8		C471405
CTD	increases(cleavage)			CASP8		C471405
CTD	increases(activity)			CASP8		C471405
CTD	increases(cleavage)			CASP8		C471405
CTD	increases(cleavage)			CASP8		C471405
CTD	affects(cotreatment)			CASP9		C471405
CTD	decreases(reaction)			CASP9		C471405
CTD	increases(cleavage)			CASP9		C471405
CTD	decreases(reaction)			CASP9		C471405
CTD	increases(activity)			CASP9		C471405
CTD	increases(cleavage)			CASP9		C471405
CTD	affects(cotreatment)			CASP9		C471405
CTD	increases(cleavage)			CASP9		C471405
CTD	affects(cotreatment)			CASP9		C471405
CTD	increases(activity)			CASP9		C471405
CTD	increases(cleavage)			CASP9		C471405
CTD	affects(cotreatment)			CASP9		C471405
CTD	increases(cleavage)			CASP9		C471405
CTD	increases(activity)			CASP9		C471405
CTD	increases(cleavage)			CASP9		C471405
CTD	decreases(expression)			CCND1		C471405
CTD	affects(cotreatment)			CCND1		C471405
CTD	decreases(expression)			CCND1		C471405
CTD	affects(cotreatment)			CCND1		C471405
CTD	decreases(expression)			CCND1		C471405
CTD	decreases(reaction)			CCND1		C471405
CTD	increases(expression)			CCND1		C471405
CTD	decreases(reaction)			CCND1		C471405
CTD	increases(expression)			CCND1		C471405
CTD	decreases(expression)			CCND1		C471405
CTD	decreases(expression)			CCND1		C471405
CTD	decreases(expression)			CCND2		C471405
CTD	affects(cotreatment)			CCND3		C471405
CTD	decreases(expression)			CCND3		C471405
CTD	decreases(expression)			CCND3		C471405
CTD	decreases(reaction)			CCNE1		C471405
CTD	increases(expression)			CCNE1		C471405
CTD	decreases(expression)			CDH1		C471405
CTD	decreases(reaction)			CDH1		C471405
CTD	increases(expression)			CDH1		C471405
CTD	increases(reaction)			CDH1		C471405
CTD	decreases(expression)			CDH2		C471405
CTD	increases(reaction)			CDH2		C471405
CTD	affects(cotreatment)			CDK4		C471405
CTD	decreases(expression)			CDK4		C471405
CTD	affects(cotreatment)			CDK6		C471405
CTD	decreases(expression)			CDK6		C471405
CTD	affects(cotreatment)			CDKN1A		C471405
CTD	decreases(response to substance)			CDKN1A		C471405
CTD	decreases(reaction)			CDKN1A		C471405
CTD	increases(expression)			CDKN1A		C471405
CTD	increases(expression)			CDKN1B		C471405
CTD	increases(reaction)			CDKN1B		C471405
CTD	increases(expression)			CDKN1B		C471405
CTD	affects(cotreatment)			CFLAR		C471405
CTD	decreases(expression)			CFLAR		C471405
CTD	increases(response to substance)			CFLAR		C471405
CTD	increases(degradation)			CFLAR		C471405
CTD	increases(response to substance)			CFLAR		C471405
CTD	decreases(reaction)			COL1A1		C471405
CTD	increases(expression)			COL1A1		C471405
CTD	decreases(reaction)			COL3A1		C471405
CTD	increases(expression)			COL3A1		C471405
CTD	decreases(reaction)			COL4A1		C471405
CTD	increases(expression)			COL4A1		C471405
CTD	affects(localization)			COX4I1		C471405
CTD	affects(cotreatment)			CRKL		C471405
CTD	decreases(reaction)			CRKL		C471405
CTD	increases(phosphorylation)			CRKL		C471405
CTD	decreases(phosphorylation)			CRKL		C471405
CTD	decreases(expression)			CTNNB1		C471405
CTD	increases(reaction)			CTNNB1		C471405
CTD	affects(localization)			CYCS		C471405
CTD	increases(expression)			CYLD		C471405
CTD	increases(expression)			DDIT3		C471405
CTD	increases(expression)			DDIT3		C471405
CTD	increases(expression)			DDIT4		C471405
CTD	increases(reaction)			DDIT4		C471405
CTD	decreases(activity)			DDIT4		C471405
CTD	decreases(expression)			DDIT4		C471405
CTD	increases(response to substance)			DDIT4		C471405
CTD	affects(localization)			DIABLO		C471405
CTD	increases(reaction)			DIABLO		C471405
CTD	decreases(reaction)			DIABLO		C471405
CTD	affects(localization)			DIABLO		C471405
CTD	affects(cotreatment)			DIABLO		C471405
CTD	affects(localization)			DIABLO		C471405
CTD	affects(cotreatment)			DIABLO		C471405
CTD	affects(localization)			DIABLO		C471405
CTD	decreases(phosphorylation)			DOK1		C471405
CTD	affects(cotreatment)			EGF		C471405
CTD	decreases(reaction)			EGF		C471405
CTD	increases(phosphorylation)			EGF		C471405
CTD	decreases(reaction)			EGF		C471405
CTD	increases(phosphorylation)			EGF		C471405
CTD	affects(cotreatment)			EIF2A		C471405
CTD	increases(phosphorylation)			EIF2A		C471405
CTD	increases(reaction)			EIF2A		C471405
CTD	increases(phosphorylation)			EIF2A		C471405
CTD	affects(binding)			EIF2AK3		C471405
CTD	affects(cotreatment)			EIF2AK3		C471405
CTD	increases(reaction)			EIF2AK3		C471405
CTD	increases(cleavage)			EIF2AK3		C471405
CTD	increases(expression)			EIF2AK3		C471405
CTD	increases(phosphorylation)			EIF2AK3		C471405
CTD	increases(phosphorylation)			EIF2AK3		C471405
CTD	decreases(reaction)			EIF4E		C471405
CTD	increases(phosphorylation)			EIF4E		C471405
CTD	decreases(phosphorylation)			EIF4E		C471405
CTD	affects(cotreatment)			EIF4EBP1		C471405
CTD	decreases(phosphorylation)			EIF4EBP1		C471405
CTD	decreases(phosphorylation)			EIF4EBP1		C471405
CTD	affects(binding)			FADD		C471405
CTD	affects(cotreatment)			FADD		C471405
CTD	increases(reaction)			FADD		C471405
CTD	decreases(expression)			FADD		C471405
CTD	increases(phosphorylation)			FADD		C471405
CTD	affects(binding)			FAS		C471405
CTD	affects(cotreatment)			FAS		C471405
CTD	increases(reaction)			FAS		C471405
CTD	decreases(expression)			FAS		C471405
CTD	increases(phosphorylation)			FAS		C471405
CTD	affects(localization)			FAS		C471405
CTD	decreases(reaction)			FAS		C471405
CTD	increases(activity)			FAS		C471405
CTD	affects(cotreatment)			FASLG		C471405
CTD	decreases(reaction)			FASLG		C471405
CTD	increases(expression)			FASLG		C471405
CTD	increases(response to substance)			FLT3		C471405
CTD	decreases(reaction)			FLT3		C471405
CTD	increases(phosphorylation)			FLT3		C471405
CTD	decreases(activity)			FLT3		C471405
CTD	decreases(activity)			FLT3		C471405
CTD	decreases(phosphorylation)			FLT3		C471405
CTD	decreases(phosphorylation)			FLT3		C471405
CTD	decreases(reaction)			FN1		C471405
CTD	increases(expression)			FN1		C471405
CTD	decreases(reaction)			GADD45B		C471405
CTD	increases(expression)			GADD45B		C471405
CTD	increases(response to substance)			GADD45B		C471405
CTD	affects(binding)			GADD45B		C471405
CTD	increases(reaction)			GADD45B		C471405
CTD	increases(localization)			GADD45B		C471405
CTD	affects(localization)			GSK3B		C471405
CTD	decreases(reaction)			GSK3B		C471405
CTD	increases(phosphorylation)			GSK3B		C471405
CTD	increases(reaction)			GSK3B		C471405
CTD	decreases(phosphorylation)			GSK3B		C471405
CTD	increases(activity)			GSK3B		C471405
CTD	affects(binding)			HSPA5		C471405
CTD	affects(cotreatment)			HSPA5		C471405
CTD	increases(reaction)			HSPA5		C471405
CTD	affects(cotreatment)			IFNA2		C471405
CTD	affects(phosphorylation)			IFNA2		C471405
CTD	affects(cotreatment)			IFNA8		C471405
CTD	affects(phosphorylation)			IFNA8		C471405
CTD	decreases(reaction)			IGF1		C471405
CTD	increases(expression)			IGF1		C471405
CTD	affects(cotreatment)			JUN		C471405
CTD	decreases(reaction)			JUN		C471405
CTD	increases(phosphorylation)			JUN		C471405
CTD	decreases(reaction)			JUN		C471405
CTD	increases(expression)			JUN		C471405
CTD	affects(cotreatment)			JUN		C471405
CTD	increases(phosphorylation)			JUN		C471405
CTD	affects(binding)			JUN		C471405
CTD	increases(reaction)			JUN		C471405
CTD	increases(localization)			JUN		C471405
CTD	increases(phosphorylation)			JUN		C471405
CTD	affects(cotreatment)			KDR		C471405
CTD	decreases(phosphorylation)			KDR		C471405
CTD	decreases(phosphorylation)			KDR		C471405
CTD	decreases(phosphorylation)			KIT		C471405
CTD	decreases(phosphorylation)			LCK		C471405
CTD	decreases(response to substance)			MAP2K1		C471405
CTD	increases(phosphorylation)			MAP2K1		C471405
CTD	affects(cotreatment)			MAP2K1		C471405
CTD	decreases(reaction)			MAP2K1		C471405
CTD	increases(phosphorylation)			MAP2K1		C471405
CTD	decreases(phosphorylation)			MAP2K1		C471405
CTD	affects(cotreatment)			MAP2K2		C471405
CTD	decreases(reaction)			MAP2K2		C471405
CTD	increases(phosphorylation)			MAP2K2		C471405
CTD	decreases(phosphorylation)			MAP2K2		C471405
CTD	decreases(response to substance)			MAPK1		C471405
CTD	increases(phosphorylation)			MAPK1		C471405
CTD	affects(phosphorylation)			MAPK1		C471405
CTD	affects(cotreatment)			MAPK1		C471405
CTD	decreases(phosphorylation)			MAPK1		C471405
CTD	affects(cotreatment)			MAPK1		C471405
CTD	affects(cotreatment)			MAPK1		C471405
CTD	decreases(reaction)			MAPK1		C471405
CTD	increases(phosphorylation)			MAPK1		C471405
CTD	affects(cotreatment)			MAPK1		C471405
CTD	decreases(phosphorylation)			MAPK1		C471405
CTD	affects(cotreatment)			MAPK1		C471405
CTD	decreases(phosphorylation)			MAPK1		C471405
CTD	decreases(reaction)			MAPK1		C471405
CTD	increases(activity)			MAPK1		C471405
CTD	decreases(reaction)			MAPK1		C471405
CTD	increases(phosphorylation)			MAPK1		C471405
CTD	decreases(reaction)			MAPK1		C471405
CTD	increases(phosphorylation)			MAPK1		C471405
CTD	decreases(activity)			MAPK1		C471405
CTD	decreases(phosphorylation)			MAPK1		C471405
CTD	decreases(activity)			MAPK1		C471405
CTD	decreases(activity)			MAPK1		C471405
CTD	decreases(phosphorylation)			MAPK1		C471405
CTD	decreases(phosphorylation)			MAPK1		C471405
CTD	decreases(expression)			MAPK14		C471405
CTD	decreases(response to substance)			MAPK3		C471405
CTD	increases(phosphorylation)			MAPK3		C471405
CTD	affects(phosphorylation)			MAPK3		C471405
CTD	affects(cotreatment)			MAPK3		C471405
CTD	decreases(phosphorylation)			MAPK3		C471405
CTD	affects(cotreatment)			MAPK3		C471405
CTD	affects(cotreatment)			MAPK3		C471405
CTD	decreases(reaction)			MAPK3		C471405
CTD	increases(phosphorylation)			MAPK3		C471405
CTD	affects(cotreatment)			MAPK3		C471405
CTD	decreases(phosphorylation)			MAPK3		C471405
CTD	affects(cotreatment)			MAPK3		C471405
CTD	decreases(phosphorylation)			MAPK3		C471405
CTD	decreases(reaction)			MAPK3		C471405
CTD	increases(phosphorylation)			MAPK3		C471405
CTD	decreases(reaction)			MAPK3		C471405
CTD	increases(activity)			MAPK3		C471405
CTD	decreases(reaction)			MAPK3		C471405
CTD	increases(phosphorylation)			MAPK3		C471405
CTD	decreases(reaction)			MAPK3		C471405
CTD	increases(phosphorylation)			MAPK3		C471405
CTD	decreases(activity)			MAPK3		C471405
CTD	decreases(phosphorylation)			MAPK3		C471405
CTD	decreases(activity)			MAPK3		C471405
CTD	decreases(activity)			MAPK3		C471405
CTD	decreases(phosphorylation)			MAPK3		C471405
CTD	decreases(phosphorylation)			MAPK3		C471405
CTD	affects(cotreatment)			MAPK8		C471405
CTD	increases(phosphorylation)			MAPK8		C471405
CTD	affects(cotreatment)			MAPK9		C471405
CTD	increases(phosphorylation)			MAPK9		C471405
CTD	affects(cotreatment)			MCL1		C471405
CTD	affects(folding)			MCL1		C471405
CTD	decreases(reaction)			MCL1		C471405
CTD	increases(activity)			MCL1		C471405
CTD	decreases(reaction)			MCL1		C471405
CTD	increases(activity)			MCL1		C471405
CTD	increases(cleavage)			MCL1		C471405
CTD	decreases(response to substance)			MCL1		C471405
CTD	affects(cotreatment)			MCL1		C471405
CTD	decreases(response to substance)			MCL1		C471405
CTD	affects(cotreatment)			MCL1		C471405
CTD	decreases(response to substance)			MCL1		C471405
CTD	affects(cotreatment)			MCL1		C471405
CTD	decreases(expression)			MCL1		C471405
CTD	decreases(expression)			MCL1		C471405
CTD	decreases(expression)			MCL1		C471405
CTD	decreases(expression)			MCL1		C471405
CTD	decreases(expression)			MCL1		C471405
CTD	increases(degradation)			MCL1		C471405
CTD	increases(degradation)			MCL1		C471405
CTD	decreases(reaction)			MKNK1		C471405
CTD	increases(phosphorylation)			MKNK1		C471405
CTD	affects(cotreatment)			MTOR		C471405
CTD	decreases(activity)			MTOR		C471405
CTD	affects(cotreatment)			MTOR		C471405
CTD	decreases(reaction)			MTOR		C471405
CTD	increases(phosphorylation)			MTOR		C471405
CTD	decreases(activity)			MTOR		C471405
CTD	decreases(phosphorylation)			MTOR		C471405
CTD	decreases(activity)			MTOR		C471405
CTD	increases(expression)			MTOR		C471405
CTD	decreases(expression)			MTOR		C471405
CTD	increases(response to substance)			MTOR		C471405
CTD	affects(cotreatment)			MYC		C471405
CTD	decreases(expression)			MYC		C471405
CTD	decreases(reaction)			MYC		C471405
CTD	increases(expression)			MYC		C471405
CTD	increases(phosphorylation)			MYC		C471405
CTD	increases(reaction)			MYC		C471405
CTD	increases(expression)			NFKBIA		C471405
CTD	affects(cotreatment)			PARP1		C471405
CTD	decreases(reaction)			PARP1		C471405
CTD	increases(cleavage)			PARP1		C471405
CTD	increases(cleavage)			PARP1		C471405
CTD	decreases(phosphorylation)			PDGFRA		C471405
CTD	affects(cotreatment)			PDGFRB		C471405
CTD	decreases(phosphorylation)			PDGFRB		C471405
CTD	decreases(activity)			PDGFRB		C471405
CTD	decreases(phosphorylation)			PDGFRB		C471405
CTD	affects(cotreatment)			PIM1		C471405
CTD	decreases(expression)			PIM1		C471405
CTD	decreases(reaction)			PIM1		C471405
CTD	increases(expression)			PIM1		C471405
CTD	decreases(expression)			PMAIP1		C471405
CTD	decreases(reaction)			PMAIP1		C471405
CTD	increases(expression)			PPP1R15A		C471405
CTD	decreases(activity)			RAF1		C471405
CTD	affects(cotreatment)			RB1		C471405
CTD	decreases(expression)			RB1		C471405
CTD	decreases(expression)			RB1		C471405
CTD	decreases(phosphorylation)			RB1		C471405
CTD	decreases(activity)			RET		C471405
CTD	increases(degradation)			RET		C471405
CTD	decreases(phosphorylation)			RPS6		C471405
CTD	increases(reaction)			RPS6		C471405
CTD	affects(cotreatment)			SMPD1		C471405
CTD	affects(localization)			SMPD1		C471405
CTD	increases(reaction)			SMPD1		C471405
CTD	increases(abundance)			SMPD1		C471405
CTD	decreases(reaction)			SNAI1		C471405
CTD	increases(expression)			SNAI1		C471405
CTD	decreases(expression)			SNAI2		C471405
CTD	increases(reaction)			SNAI2		C471405
CTD	decreases(localization)			SOX17		C471405
CTD	decreases(reaction)			SRC		C471405
CTD	increases(phosphorylation)			SRC		C471405
CTD	decreases(activity)			SRC		C471405
CTD	decreases(phosphorylation)			STAT3		C471405
CTD	decreases(reaction)			STAT3		C471405
CTD	increases(phosphorylation)			STAT3		C471405
CTD	decreases(reaction)			STAT3		C471405
CTD	increases(phosphorylation)			STAT3		C471405
CTD	decreases(reaction)			STAT3		C471405
CTD	increases(phosphorylation)			STAT3		C471405
CTD	decreases(activity)			STAT3		C471405
CTD	decreases(phosphorylation)			STAT3		C471405
CTD	decreases(phosphorylation)			STAT3		C471405
CTD	decreases(phosphorylation)			STAT5A		C471405
CTD	decreases(activity)			STAT5A		C471405
CTD	decreases(expression)			TGFB1		C471405
CTD	decreases(reaction)			TGFB1		C471405
CTD	increases(activity)			TGFB1		C471405
CTD	increases(expression)			TGFB1		C471405
CTD	increases(phosphorylation)			TGFB1		C471405
CTD	decreases(activity)			TGFB1		C471405
CTD	decreases(expression)			TJP1		C471405
CTD	decreases(reaction)			TJP1		C471405
CTD	increases(expression)			TNFRSF10B		C471405
CTD	affects(cotreatment)			TNFSF10		C471405
CTD	affects(folding)			TNFSF10		C471405
CTD	decreases(reaction)			TNFSF10		C471405
CTD	increases(activity)			TNFSF10		C471405
CTD	affects(localization)			TNFSF10		C471405
CTD	increases(cleavage)			TNFSF10		C471405
CTD	increases(reaction)			TNFSF10		C471405
CTD	decreases(expression)			TNFSF10		C471405
CTD	affects(cotreatment)			TNFSF10		C471405
CTD	increases(cleavage)			TNFSF10		C471405
CTD	increases(response to substance)			TNFSF10		C471405
CTD	increases(degradation)			TNFSF10		C471405
CTD	increases(response to substance)			TNFSF10		C471405
CTD	decreases(activity)			TNFSF10		C471405
CTD	increases(expression)			TNFSF10		C471405
CTD	increases(response to substance)			TNFSF10		C471405
CTD	increases(phosphorylation)			TP53		C471405
CTD	increases(reaction)			TP53		C471405
CTD	decreases(expression)			VIM		C471405
CTD	increases(reaction)			VIM		C471405
CTD	decreases(reaction)			VIM		C471405
CTD	increases(expression)			VIM		C471405
CTD	increases(splicing)			XBP1		C471405
CTD	affects(cotreatment)			XIAP		C471405
CTD	increases(cleavage)			XIAP		C471405
CTD	decreases(expression)			XIAP		C471405
CTD	increases(cleavage)			XIAP		C471405
PubChem	None	uM	1.500	DDR1	-	GI(Protien) :
PubChem	None	uM	6.600	DDR2	-	GI(Protien) :
PubChem	None	uM		EZH2	-	GI(Protien) :
PubChem	Potency	uM	8.414	GMNN	-	GI(Protien) :
PubChem	None	uM	7.400	RET	-	GI(Protien) :
PubChem	None	uM		STK16	-	GI(Protien) :
PubChem	Potency	uM	3.162	TDP1	-	GI(Protien) :
PubChem	Potency	uM	5.623	TDP1	-	GI(Protien) :
PubChem	Potency	uM	27.404	YES1		GI(Protien) :
PubChem	Potency	uM	34.499	YES1		GI(Protien) :
PubChem	None	uM	6.300	ZAK	-	GI(Protien) :
ChEMBL	Activity	-		PTPN6	-	Target : CHEMBL3166
ChEMBL	Inhibition	-		RET	-	Target : CHEMBL2041

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