Tan Lab | DSigDB

Gene Set: D4 : CTD - methylparaoxon

Collection

D4 : CTD

Chemical Name

methylparaoxon ( From PubChem : PARAOXON-METHYL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
247.142 g/mol	0	4	2.8977	True

Structure

InChI

InChI=1S/C8H10NO6P/c1-13-16(12,14-2)15-8-5-3-7(4-6-8)9(10)11/h3-6H,1-2H3

InChIKey

Links

Gene (15 / 24)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			ACHE		C008480
CTD	decreases(reaction)			ACHE		C008480
CTD	decreases(activity)			ACHE		C008480
CTD	affects(cotreatment)			AKR1C1		C008480
CTD	affects(response to substance)			AKR1C1		C008480
CTD	increases(expression)			AKR1C1		C008480
CTD	affects(cotreatment)			AKR1C2		C008480
CTD	affects(response to substance)			AKR1C2		C008480
CTD	increases(expression)			AKR1C2		C008480
CTD	affects(binding)			ALB		C008480
CTD	affects(activity)			BCHE		C008480
CTD	increases(expression)			CDKN1A		C008480
CTD	decreases(reaction)			CYP1A1		C008480
CTD	increases(expression)			CYP1A1		C008480
CTD	increases(expression)			GADD45A		C008480
CTD	increases(expression)			MDM2		C008480
CTD	decreases(expression)			MKI67		C008480
CTD	increases(expression)			TP53		C008480
PubChem	Ratio Potency (uM)	uM	19.494	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	34.376	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	17.374	PPARG	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :

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