Tan Lab | DSigDB

Gene Set: D4 : CTD - dehydroxymethylepoxyquinomicin

Collection

D4 : CTD

Chemical Name

dehydroxymethylepoxyquinomicin ( From PubChem : DEHYDROXYMETHYLEPOXYQUINOMICIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
261.23 g/mol	3	6	0.1078	True

Structure

InChI

InChI=1S/C13H11NO5/c15-8-4-2-1-3-6(8)13(18)14-7-5-9(16)11-12(19-11)10(7)17/h1-5,10-12,15,17H,(H,14,18)/t10-,11+,12-/m0/s1

InChIKey

Links

Gene (13 / 25)

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Source	Type	Unit	Gene	PMID	Other
CTD	decreases(expression)		BIRC2		C464444
CTD	decreases(expression)		BIRC3		C464444
CTD	affects(cotreatment)		BIRC5		C464444
CTD	decreases(expression)		BIRC5		C464444
CTD	decreases(reaction)		CASP3		C464444
CTD	increases(cleavage)		CASP3		C464444
CTD	decreases(reaction)		CASP6		C464444
CTD	increases(cleavage)		CASP6		C464444
CTD	decreases(reaction)		CASP8		C464444
CTD	increases(cleavage)		CASP8		C464444
CTD	decreases(reaction)		CASP9		C464444
CTD	increases(cleavage)		CASP9		C464444
CTD	affects(cotreatment)		CFLAR		C464444
CTD	decreases(expression)		CFLAR		C464444
CTD	decreases(localization)		NFKB1		C464444
CTD	decreases(reaction)		PARP1		C464444
CTD	increases(cleavage)		PARP1		C464444
CTD	decreases(activity)		RELA		C464444
CTD	decreases(localization)		RELA		C464444
CTD	affects(cotreatment)		TNF		C464444
CTD	decreases(expression)		TNF		C464444
CTD	decreases(expression)		XIAP		C464444
ChEMBL	Activity	-	NFKB1	-	Target : CHEMBL3251
ChEMBL	Activity	-	NFKB1	-	Target : CHEMBL3251
ChEMBL	Activity	-	RELA	-	Target : CHEMBL5533

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