Gene Set: D4 : CTD - anthra(1,9-cd)pyrazol-6(2H)-one

Collection	D4 : CTD
Chemical Name	anthra(1,9-cd)pyrazol-6(2H)-one ( From PubChem : 1,9-PYRAZOLOANTHRONE )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 220.226 g/mol 1 2 2.6673 True
Structure
InChI	InChI=1S/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7H,(H,15,16)
InChIKey	ACPOUJIDANTYHO-UHFFFAOYSA-N
Links
Gene (181 / 881) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(reaction) ABCB1 C432165 CTD increases(expression) ABCB1 C432165 CTD affects(binding) AHR C432165 CTD increases(activity) AHR C432165 CTD affects(localization) AIFM1 C432165 CTD decreases(reaction) AIFM1 C432165 CTD decreases(reaction) AKT1 C432165 CTD increases(activity) AKT1 C432165 CTD decreases(activity) AKT1 C432165 CTD decreases(phosphorylation) AKT1 C432165 CTD decreases(reaction) AKT1 C432165 CTD decreases(reaction) AKT1 C432165 CTD increases(phosphorylation) AKT1 C432165 CTD decreases(expression) ALOX5 C432165 CTD decreases(reaction) APOA1 C432165 CTD increases(expression) APOA1 C432165 CTD decreases(reaction) APOD C432165 CTD increases(expression) APOD C432165 CTD affects(cotreatment) APP C432165 CTD decreases(expression) APP C432165 CTD decreases(reaction) APP C432165 CTD decreases(expression) AQP1 C432165 CTD decreases(reaction) AQP1 C432165 CTD decreases(reaction) ATF2 C432165 CTD decreases(response to substance) ATF2 C432165 CTD decreases(reaction) ATF2 C432165 CTD increases(phosphorylation) ATF2 C432165 CTD increases(activity) ATF2 C432165 CTD increases(phosphorylation) ATF2 C432165 CTD decreases(reaction) ATF2 C432165 CTD increases(phosphorylation) ATF2 C432165 CTD decreases(reaction) ATF2 C432165 CTD increases(expression) ATF2 C432165 CTD decreases(reaction) ATF3 C432165 CTD increases(phosphorylation) ATF3 C432165 CTD decreases(reaction) BAD C432165 CTD increases(expression) BAD C432165 CTD decreases(reaction) BAG3 C432165 CTD increases(expression) BAG3 C432165 CTD decreases(reaction) BAK1 C432165 CTD increases(activity) BAK1 C432165 CTD affects(localization) BAX C432165 CTD decreases(reaction) BAX C432165 CTD decreases(reaction) BAX C432165 CTD increases(activity) BAX C432165 CTD affects(localization) BAX C432165 CTD decreases(reaction) BAX C432165 CTD decreases(reaction) BAX C432165 CTD increases(expression) BAX C432165 CTD increases(activity) BAX C432165 CTD increases(localization) BAX C432165 CTD increases(reaction) BAX C432165 CTD increases(expression) BAX C432165 CTD affects(reaction) BAX C432165 CTD decreases(reaction) BCL2 C432165 CTD increases(phosphorylation) BCL2 C432165 CTD decreases(expression) BCL2 C432165 CTD decreases(reaction) BCL2 C432165 CTD decreases(reaction) BCL2 C432165 CTD increases(phosphorylation) BCL2 C432165 CTD decreases(reaction) BCL2 C432165 CTD increases(phosphorylation) BCL2 C432165 CTD decreases(reaction) BCL2 C432165 CTD increases(phosphorylation) BCL2 C432165 CTD decreases(expression) BCL2 C432165 CTD decreases(reaction) BCL2 C432165 CTD decreases(expression) BCL2 C432165 CTD decreases(reaction) BCL2 C432165 CTD decreases(expression) BCL2 C432165 CTD decreases(reaction) BCL2 C432165 CTD decreases(expression) BCL2 C432165 CTD decreases(reaction) BCL2 C432165 CTD decreases(expression) BCL2L1 C432165 CTD decreases(reaction) BCL2L1 C432165 CTD decreases(expression) BCL2L1 C432165 CTD decreases(reaction) BCL2L1 C432165 CTD affects(cotreatment) BCL2L1 C432165 CTD decreases(reaction) BCL2L1 C432165 CTD increases(phosphorylation) BCL2L1 C432165 CTD decreases(reaction) BCL2L11 C432165 CTD increases(degradation) BCL2L11 C432165 CTD decreases(reaction) BCL2L11 C432165 CTD increases(expression) BCL2L11 C432165 CTD decreases(reaction) BDNF C432165 CTD increases(expression) BDNF C432165 CTD increases(cleavage) BID C432165 CTD increases(reaction) BID C432165 CTD increases(expression) BIRC2 C432165 CTD increases(reaction) BIRC2 C432165 CTD decreases(expression) BIRC5 C432165 CTD decreases(reaction) BIRC5 C432165 CTD decreases(expression) BIRC5 C432165 CTD decreases(reaction) BIRC5 C432165 CTD decreases(expression) BIRC5 C432165 CTD decreases(reaction) BIRC5 C432165 CTD decreases(reaction) BNIP3 C432165 CTD increases(expression) BNIP3 C432165 CTD decreases(activity) CASP2 C432165 CTD decreases(reaction) CASP3 C432165 CTD increases(cleavage) CASP3 C432165 CTD decreases(reaction) CASP3 C432165 CTD increases(expression) CASP3 C432165 CTD decreases(reaction) CASP3 C432165 CTD increases(activity) CASP3 C432165 CTD decreases(reaction) CASP3 C432165 CTD increases(expression) CASP3 C432165 CTD decreases(reaction) CASP3 C432165 CTD increases(activity) CASP3 C432165 CTD decreases(reaction) CASP3 C432165 CTD increases(cleavage) CASP3 C432165 CTD decreases(reaction) CASP3 C432165 CTD increases(expression) CASP3 C432165 CTD decreases(reaction) CASP3 C432165 CTD increases(activity) CASP3 C432165 CTD decreases(reaction) CASP3 C432165 CTD increases(cleavage) CASP3 C432165 CTD decreases(reaction) CASP3 C432165 CTD increases(activity) CASP3 C432165 CTD decreases(reaction) CASP3 C432165 CTD increases(activity) CASP3 C432165 CTD increases(cleavage) CASP3 C432165 CTD affects(cotreatment) CASP3 C432165 CTD decreases(reaction) CASP3 C432165 CTD increases(cleavage) CASP3 C432165 CTD decreases(reaction) CASP3 C432165 CTD increases(activity) CASP3 C432165 CTD decreases(reaction) CASP3 C432165 CTD increases(activity) CASP3 C432165 CTD affects(cotreatment) CASP3 C432165 CTD decreases(reaction) CASP3 C432165 CTD increases(cleavage) CASP3 C432165 CTD affects(cotreatment) CASP3 C432165 CTD decreases(reaction) CASP3 C432165 CTD increases(activity) CASP3 C432165 CTD increases(activity) CASP3 C432165 CTD increases(cleavage) CASP3 C432165 CTD increases(reaction) CASP3 C432165 CTD decreases(activity) CASP3 C432165 CTD increases(activity) CASP3 C432165 CTD decreases(reaction) CASP4 C432165 CTD increases(cleavage) CASP4 C432165 CTD decreases(reaction) CASP6 C432165 CTD increases(cleavage) CASP6 C432165 CTD decreases(reaction) CASP6 C432165 CTD increases(activity) CASP6 C432165 CTD decreases(reaction) CASP6 C432165 CTD increases(activity) CASP6 C432165 CTD increases(cleavage) CASP6 C432165 CTD decreases(reaction) CASP7 C432165 CTD increases(activity) CASP7 C432165 CTD increases(cleavage) CASP7 C432165 CTD decreases(reaction) CASP8 C432165 CTD increases(expression) CASP8 C432165 CTD decreases(reaction) CASP8 C432165 CTD increases(activity) CASP8 C432165 CTD affects(cotreatment) CASP8 C432165 CTD decreases(reaction) CASP8 C432165 CTD increases(cleavage) CASP8 C432165 CTD decreases(reaction) CASP8 C432165 CTD increases(cleavage) CASP8 C432165 CTD affects(cotreatment) CASP8 C432165 CTD decreases(reaction) CASP8 C432165 CTD increases(cleavage) CASP8 C432165 CTD increases(activity) CASP8 C432165 CTD increases(reaction) CASP8 C432165 CTD increases(activity) CASP8 C432165 CTD increases(cleavage) CASP8 C432165 CTD increases(reaction) CASP8 C432165 CTD decreases(reaction) CASP9 C432165 CTD increases(cleavage) CASP9 C432165 CTD decreases(reaction) CASP9 C432165 CTD increases(expression) CASP9 C432165 CTD decreases(reaction) CASP9 C432165 CTD increases(activity) CASP9 C432165 CTD decreases(reaction) CASP9 C432165 CTD increases(cleavage) CASP9 C432165 CTD decreases(reaction) CASP9 C432165 CTD increases(activity) CASP9 C432165 CTD decreases(reaction) CASP9 C432165 CTD increases(activity) CASP9 C432165 CTD increases(activity) CASP9 C432165 CTD decreases(expression) CAT C432165 CTD increases(reaction) CAT C432165 CTD increases(expression) CCL8 C432165 CTD increases(reaction) CCL8 C432165 CTD decreases(reaction) CCNB1 C432165 CTD increases(expression) CCNB1 C432165 CTD decreases(reaction) CCND1 C432165 CTD increases(expression) CCND1 C432165 CTD decreases(reaction) CD14 C432165 CTD increases(expression) CD14 C432165 CTD decreases(reaction) CD14 C432165 CTD increases(expression) CD14 C432165 CTD decreases(expression) CD207 C432165 CTD increases(reaction) CD207 C432165 CTD affects(expression) CDC25C C432165 CTD decreases(reaction) CDC25C C432165 CTD decreases(expression) CDH1 C432165 CTD increases(reaction) CDH1 C432165 CTD decreases(reaction) CDK1 C432165 CTD increases(expression) CDK1 C432165 CTD decreases(expression) CDK2 C432165 CTD decreases(reaction) CDK2 C432165 CTD decreases(activity) CDK2 C432165 CTD increases(expression) CDKN1A C432165 CTD increases(reaction) CDKN1A C432165 CTD increases(expression) CDKN1A C432165 CTD increases(reaction) CDKN1A C432165 CTD increases(expression) CDKN1A C432165 CTD increases(reaction) CDKN1A C432165 CTD increases(expression) CDKN1A C432165 CTD decreases(reaction) CEBPA C432165 CTD increases(activity) CEBPA C432165 CTD increases(localization) CEBPA C432165 CTD decreases(reaction) CEBPB C432165 CTD increases(expression) CEBPB C432165 CTD decreases(reaction) CEBPB C432165 CTD increases(activity) CEBPB C432165 CTD increases(localization) CEBPB C432165 CTD decreases(reaction) CEBPD C432165 CTD increases(activity) CEBPD C432165 CTD increases(localization) CEBPD C432165 CTD decreases(reaction) CSF2 C432165 CTD increases(secretion) CSF2 C432165 CTD decreases(activity) CSNK1D C432165 CTD decreases(reaction) CXCL10 C432165 CTD increases(expression) CXCL10 C432165 CTD increases(expression) CXCL3 C432165 CTD increases(reaction) CXCL3 C432165 CTD decreases(reaction) CXCL8 C432165 CTD increases(reaction) CXCL8 C432165 CTD increases(secretion) CXCL8 C432165 CTD decreases(reaction) CXCL8 C432165 CTD increases(expression) CXCL8 C432165 CTD increases(secretion) CXCL8 C432165 CTD decreases(reaction) CXCL8 C432165 CTD increases(expression) CXCL8 C432165 CTD decreases(reaction) CXCL8 C432165 CTD increases(expression) CXCL8 C432165 CTD decreases(reaction) CXCL8 C432165 CTD increases(secretion) CXCL8 C432165 CTD affects(cotreatment) CXCL8 C432165 CTD decreases(reaction) CXCL8 C432165 CTD increases(expression) CXCL8 C432165 CTD decreases(reaction) CXCL8 C432165 CTD increases(expression) CXCL8 C432165 CTD decreases(response to substance) CXCL8 C432165 CTD increases(secretion) CXCL8 C432165 CTD decreases(reaction) CXCL8 C432165 CTD increases(expression) CXCL8 C432165 CTD affects(localization) CYCS C432165 CTD decreases(reaction) CYCS C432165 CTD affects(localization) CYCS C432165 CTD increases(reaction) CYCS C432165 CTD decreases(expression) CYP17A1 C432165 CTD decreases(reaction) CYP17A1 C432165 CTD increases(expression) CYP17A1 C432165 CTD decreases(reaction) CYP19A1 C432165 CTD increases(expression) CYP19A1 C432165 CTD decreases(reaction) CYP1A1 C432165 CTD increases(expression) CYP1A1 C432165 CTD decreases(reaction) CYP1A2 C432165 CTD increases(expression) CYP1A2 C432165 CTD decreases(reaction) CYP3A4 C432165 CTD increases(expression) CYP3A4 C432165 CTD decreases(reaction) DDIT3 C432165 CTD increases(expression) DDIT3 C432165 CTD decreases(reaction) DDIT3 C432165 CTD increases(expression) DDIT3 C432165 CTD decreases(reaction) DDIT3 C432165 CTD increases(expression) DDIT3 C432165 CTD affects(cotreatment) DIO1 C432165 CTD decreases(expression) DIO1 C432165 CTD decreases(reaction) DIO1 C432165 CTD decreases(activity) DYRK1A C432165 CTD decreases(reaction) EDN1 C432165 CTD increases(expression) EDN1 C432165 CTD decreases(reaction) EGF C432165 CTD decreases(response to substance) EGF C432165 CTD increases(reaction) EGF C432165 CTD increases(expression) EGF C432165 CTD increases(reaction) EGF C432165 CTD decreases(expression) EGFR C432165 CTD decreases(reaction) EGR1 C432165 CTD increases(expression) EGR1 C432165 CTD decreases(reaction) ELK1 C432165 CTD increases(phosphorylation) ELK1 C432165 CTD decreases(reaction) ELK1 C432165 CTD increases(phosphorylation) ELK1 C432165 CTD decreases(reaction) ELK1 C432165 CTD increases(phosphorylation) ELK1 C432165 CTD decreases(reaction) EPOR C432165 CTD increases(expression) EPOR C432165 CTD decreases(reaction) ERN1 C432165 CTD increases(expression) ERN1 C432165 CTD decreases(reaction) ETFA C432165 CTD increases(expression) ETFA C432165 CTD affects(cotreatment) F2 C432165 CTD decreases(reaction) F2 C432165 CTD increases(expression) F2 C432165 CTD decreases(reaction) F3 C432165 CTD increases(expression) F3 C432165 CTD affects(cotreatment) F3 C432165 CTD decreases(reaction) F3 C432165 CTD increases(expression) F3 C432165 CTD decreases(reaction) F3 C432165 CTD increases(expression) F3 C432165 CTD decreases(reaction) FADD C432165 CTD increases(phosphorylation) FADD C432165 CTD decreases(reaction) FADD C432165 CTD increases(phosphorylation) FADD C432165 CTD decreases(reaction) FADD C432165 CTD increases(phosphorylation) FADD C432165 CTD decreases(phosphorylation) FADD C432165 CTD decreases(reaction) FAS C432165 CTD increases(expression) FAS C432165 CTD increases(activity) FAS C432165 CTD increases(cleavage) FAS C432165 CTD increases(reaction) FAS C432165 CTD increases(expression) FAS C432165 CTD affects(cotreatment) FASLG C432165 CTD decreases(reaction) FASLG C432165 CTD increases(expression) FASLG C432165 CTD decreases(expression) FGF19 C432165 CTD decreases(reaction) FGF19 C432165 CTD decreases(reaction) FGF2 C432165 CTD increases(secretion) FGF2 C432165 CTD decreases(reaction) FGF2 C432165 CTD increases(expression) FGF2 C432165 CTD decreases(reaction) FGF7 C432165 CTD increases(expression) FGF7 C432165 CTD decreases(reaction) FGF7 C432165 CTD increases(secretion) FGF7 C432165 CTD affects(cotreatment) FOS C432165 CTD affects(localization) FOS C432165 CTD decreases(reaction) FOS C432165 CTD decreases(reaction) GABPA C432165 CTD increases(expression) GABPA C432165 CTD decreases(reaction) GADD45A C432165 CTD increases(expression) GADD45A C432165 CTD decreases(reaction) GADD45B C432165 CTD increases(expression) GADD45B C432165 CTD decreases(reaction) GCH1 C432165 CTD increases(expression) GCH1 C432165 CTD decreases(reaction) GCLC C432165 CTD increases(expression) GCLC C432165 CTD decreases(activity) GCLM C432165 CTD increases(expression) GDF15 C432165 CTD increases(reaction) GDF15 C432165 CTD decreases(reaction) HIF1A C432165 CTD increases(activity) HIF1A C432165 CTD increases(expression) HIF1A C432165 CTD increases(stability) HIF1A C432165 CTD decreases(reaction) HIST3H3 C432165 CTD increases(phosphorylation) HIST3H3 C432165 CTD decreases(reaction) HMOX1 C432165 CTD increases(expression) HMOX1 C432165 CTD decreases(reaction) HMOX1 C432165 CTD increases(activity) HMOX1 C432165 CTD increases(expression) HMOX1 C432165 CTD decreases(reaction) HMOX1 C432165 CTD increases(expression) HMOX1 C432165 CTD decreases(reaction) HMOX1 C432165 CTD increases(expression) HMOX1 C432165 CTD decreases(reaction) HMOX1 C432165 CTD increases(expression) HMOX1 C432165 CTD decreases(reaction) HMOX1 C432165 CTD increases(expression) HMOX1 C432165 CTD decreases(reaction) HMOX1 C432165 CTD increases(expression) HMOX1 C432165 CTD decreases(reaction) HMOX1 C432165 CTD increases(expression) HMOX1 C432165 CTD increases(reaction) HMOX1 C432165 CTD decreases(expression) HNF4A C432165 CTD decreases(reaction) HNF4A C432165 CTD increases(expression) HNF4A C432165 CTD decreases(reaction) HSF1 C432165 CTD increases(phosphorylation) HSF1 C432165 CTD decreases(reaction) HSPA5 C432165 CTD increases(expression) HSPA5 C432165 CTD decreases(reaction) HSPA6 C432165 CTD increases(expression) HSPA6 C432165 CTD affects(binding) HSPA9 C432165 CTD affects(cotreatment) HSPA9 C432165 CTD increases(reaction) HSPA9 C432165 CTD decreases(reaction) ICAM1 C432165 CTD increases(expression) ICAM1 C432165 CTD decreases(reaction) ICAM1 C432165 CTD increases(expression) ICAM1 C432165 CTD decreases(reaction) IFNG C432165 CTD increases(expression) IFNG C432165 CTD decreases(reaction) IL12B C432165 CTD increases(secretion) IL12B C432165 CTD decreases(reaction) IL1A C432165 CTD increases(expression) IL1A C432165 CTD decreases(reaction) IL1A C432165 CTD increases(expression) IL1A C432165 CTD increases(phosphorylation) IL1A C432165 CTD increases(secretion) IL1A C432165 CTD increases(reaction) IL1A C432165 CTD decreases(reaction) IL1B C432165 CTD increases(secretion) IL1B C432165 CTD increases(reaction) IL1B C432165 CTD decreases(reaction) IL1B C432165 CTD increases(expression) IL1B C432165 CTD decreases(reaction) IL1B C432165 CTD increases(activity) IL1B C432165 CTD decreases(reaction) IL1B C432165 CTD increases(activity) IL1B C432165 CTD increases(expression) IL1B C432165 CTD decreases(reaction) IL1B C432165 CTD increases(expression) IL1B C432165 CTD decreases(reaction) IL1B C432165 CTD increases(expression) IL1B C432165 CTD increases(expression) IL1B C432165 CTD decreases(reaction) IL1B C432165 CTD increases(expression) IL1B C432165 CTD increases(phosphorylation) IL1B C432165 CTD increases(secretion) IL1B C432165 CTD increases(secretion) IL1B C432165 CTD increases(secretion) IL1B C432165 CTD decreases(reaction) IL1B C432165 CTD increases(expression) IL1B C432165 CTD decreases(reaction) IL1B C432165 CTD increases(expression) IL1B C432165 CTD decreases(reaction) IL1B C432165 CTD increases(expression) IL1B C432165 CTD affects(cotreatment) IL1B C432165 CTD decreases(reaction) IL1B C432165 CTD increases(expression) IL1B C432165 CTD affects(cotreatment) IL1B C432165 CTD decreases(expression) IL1B C432165 CTD decreases(reaction) IL1B C432165 CTD decreases(reaction) IL6 C432165 CTD increases(expression) IL6 C432165 CTD decreases(reaction) IL6 C432165 CTD increases(expression) IL6 C432165 CTD increases(secretion) IL6 C432165 CTD decreases(reaction) IL6 C432165 CTD increases(secretion) IL6 C432165 CTD decreases(reaction) IL6 C432165 CTD increases(expression) IL6 C432165 CTD decreases(reaction) IL6 C432165 CTD increases(expression) IL6 C432165 CTD affects(cotreatment) IL6 C432165 CTD decreases(reaction) IL6 C432165 CTD increases(expression) IL6 C432165 CTD decreases(reaction) INSR C432165 CTD increases(phosphorylation) INSR C432165 CTD increases(expression) ITGAM C432165 CTD increases(reaction) ITGAM C432165 CTD affects(cotreatment) JUN C432165 CTD affects(localization) JUN C432165 CTD decreases(reaction) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(expression) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(expression) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(expression) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(phosphorylation) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(phosphorylation) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(phosphorylation) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(phosphorylation) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(phosphorylation) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(phosphorylation) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(activity) JUN C432165 CTD increases(expression) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(expression) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(phosphorylation) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(phosphorylation) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(activity) JUN C432165 CTD increases(phosphorylation) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(phosphorylation) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(phosphorylation) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(phosphorylation) JUN C432165 CTD affects(cotreatment) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(phosphorylation) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(expression) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(phosphorylation) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(expression) JUN C432165 CTD affects(localization) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(activity) JUN C432165 CTD increases(phosphorylation) JUN C432165 CTD increases(expression) JUN C432165 CTD increases(reaction) JUN C432165 CTD decreases(phosphorylation) JUN C432165 CTD affects(binding) JUN C432165 CTD decreases(phosphorylation) JUN C432165 CTD decreases(reaction) JUN C432165 CTD affects(cotreatment) JUN C432165 CTD decreases(reaction) JUN C432165 CTD increases(expression) JUN C432165 CTD increases(phosphorylation) JUN C432165 CTD decreases(reaction) MAP3K1 C432165 CTD increases(expression) MAP3K1 C432165 CTD decreases(reaction) MAPK1 C432165 CTD increases(phosphorylation) MAPK1 C432165 CTD decreases(reaction) MAPK1 C432165 CTD increases(phosphorylation) MAPK1 C432165 CTD decreases(reaction) MAPK1 C432165 CTD increases(phosphorylation) MAPK1 C432165 CTD decreases(reaction) MAPK14 C432165 CTD increases(phosphorylation) MAPK14 C432165 CTD decreases(reaction) MAPK3 C432165 CTD increases(phosphorylation) MAPK3 C432165 CTD decreases(reaction) MAPK3 C432165 CTD increases(phosphorylation) MAPK3 C432165 CTD decreases(reaction) MAPK3 C432165 CTD increases(phosphorylation) MAPK3 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(activity) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(expression) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD affects(cotreatment) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD affects(cotreatment) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(activity) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(activity) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD increases(reaction) MAPK8 C432165 CTD decreases(reaction) MAPK8 C432165 CTD increases(phosphorylation) MAPK8 C432165 CTD decreases(activity) MAPK8 C432165 CTD decreases(reaction) MAPK9 C432165 CTD increases(phosphorylation) MAPK9 C432165 CTD decreases(reaction) MAPK9 C432165 CTD increases(phosphorylation) MAPK9 C432165 CTD decreases(reaction) MAPK9 C432165 CTD increases(phosphorylation) MAPK9 C432165 CTD decreases(reaction) MAPK9 C432165 CTD increases(phosphorylation) MAPK9 C432165 CTD decreases(reaction) MAPK9 C432165 CTD increases(phosphorylation) MAPK9 C432165 CTD decreases(reaction) MAPK9 C432165 CTD increases(phosphorylation) MAPK9 C432165 CTD decreases(reaction) MAPK9 C432165 CTD increases(phosphorylation) MAPK9 C432165 CTD decreases(reaction) MAPK9 C432165 CTD increases(phosphorylation) MAPK9 C432165 CTD decreases(reaction) MAPK9 C432165 CTD increases(activity) MAPK9 C432165 CTD increases(phosphorylation) MAPK9 C432165 CTD decreases(reaction) MAPK9 C432165 CTD increases(phosphorylation) MAPK9 C432165 CTD decreases(activity) MAPK9 C432165 CTD decreases(expression) MCM2 C432165 CTD decreases(reaction) MCM2 C432165 CTD decreases(reaction) MIF C432165 CTD increases(phosphorylation) MIF C432165 CTD decreases(reaction) MMP1 C432165 CTD increases(expression) MMP1 C432165 CTD decreases(reaction) MMP1 C432165 CTD increases(expression) MMP1 C432165 CTD decreases(reaction) MMP12 C432165 CTD increases(activity) MMP12 C432165 CTD increases(expression) MMP12 C432165 CTD decreases(reaction) MMP13 C432165 CTD increases(expression) MMP13 C432165 CTD decreases(reaction) MMP13 C432165 CTD increases(expression) MMP13 C432165 CTD decreases(reaction) MMP14 C432165 CTD increases(expression) MMP14 C432165 CTD decreases(reaction) MMP2 C432165 CTD increases(activity) MMP2 C432165 CTD increases(expression) MMP2 C432165 CTD decreases(reaction) MMP3 C432165 CTD increases(expression) MMP3 C432165 CTD decreases(reaction) MMP3 C432165 CTD increases(expression) MMP3 C432165 CTD decreases(reaction) MMP3 C432165 CTD increases(expression) MMP3 C432165 CTD decreases(reaction) MMP3 C432165 CTD increases(expression) MMP3 C432165 CTD affects(reaction) MMP9 C432165 CTD increases(expression) MMP9 C432165 CTD decreases(reaction) MMP9 C432165 CTD increases(activity) MMP9 C432165 CTD decreases(reaction) MMP9 C432165 CTD increases(activity) MMP9 C432165 CTD increases(secretion) MMP9 C432165 CTD decreases(reaction) MMP9 C432165 CTD increases(secretion) MMP9 C432165 CTD decreases(reaction) MMP9 C432165 CTD increases(activity) MMP9 C432165 CTD increases(expression) MMP9 C432165 CTD decreases(activity) MMP9 C432165 CTD increases(reaction) MMP9 C432165 CTD increases(expression) MYC C432165 CTD affects(reaction) MYC C432165 CTD decreases(reaction) NFE2L2 C432165 CTD increases(activity) NFE2L2 C432165 CTD increases(expression) NFE2L2 C432165 CTD affects(localization) NFE2L2 C432165 CTD decreases(reaction) NFE2L2 C432165 CTD decreases(reaction) NFKB1 C432165 CTD increases(localization) NFKB1 C432165 CTD decreases(reaction) NFKBIA C432165 CTD increases(phosphorylation) NFKBIA C432165 CTD decreases(reaction) NGF C432165 CTD increases(expression) NGF C432165 CTD decreases(reaction) NOS2 C432165 CTD increases(chemical synthesis) NOS2 C432165 CTD increases(expression) NOS2 C432165 CTD decreases(reaction) NOS2 C432165 CTD increases(expression) NOS2 C432165 CTD decreases(reaction) NR0B2 C432165 CTD increases(expression) NR0B2 C432165 CTD increases(expression) NR1H3 C432165 CTD decreases(reaction) PARP1 C432165 CTD increases(cleavage) PARP1 C432165 CTD decreases(reaction) PARP1 C432165 CTD increases(cleavage) PARP1 C432165 CTD decreases(reaction) PARP1 C432165 CTD increases(cleavage) PARP1 C432165 CTD decreases(reaction) PARP1 C432165 CTD increases(cleavage) PARP1 C432165 CTD decreases(reaction) PARP1 C432165 CTD increases(cleavage) PARP1 C432165 CTD affects(cotreatment) PARP1 C432165 CTD decreases(reaction) PARP1 C432165 CTD increases(cleavage) PARP1 C432165 CTD affects(cotreatment) PARP1 C432165 CTD increases(cleavage) PARP1 C432165 CTD increases(response to substance) PARP1 C432165 CTD decreases(reaction) PLAU C432165 CTD increases(activity) PLAU C432165 CTD increases(expression) PLAU C432165 CTD decreases(reaction) PLAUR C432165 CTD increases(expression) PLAUR C432165 CTD decreases(expression) PON1 C432165 CTD decreases(reaction) PON1 C432165 CTD decreases(expression) PPARA C432165 CTD decreases(reaction) PPARA C432165 CTD decreases(reaction) PPARD C432165 CTD increases(expression) PPARD C432165 CTD decreases(reaction) PRF1 C432165 CTD increases(expression) PRF1 C432165 CTD decreases(reaction) PRKCD C432165 CTD increases(phosphorylation) PRKCD C432165 CTD decreases(reaction) PTEN C432165 CTD increases(expression) PTEN C432165 CTD decreases(reaction) PTGS2 C432165 CTD increases(expression) PTGS2 C432165 CTD decreases(reaction) PTGS2 C432165 CTD increases(expression) PTGS2 C432165 CTD decreases(reaction) PTGS2 C432165 CTD increases(expression) PTGS2 C432165 CTD decreases(reaction) PTGS2 C432165 CTD increases(chemical synthesis) PTGS2 C432165 CTD increases(expression) PTGS2 C432165 CTD decreases(reaction) PTGS2 C432165 CTD increases(expression) PTGS2 C432165 CTD decreases(reaction) PTGS2 C432165 CTD increases(expression) PTGS2 C432165 CTD decreases(reaction) PTGS2 C432165 CTD increases(expression) PTGS2 C432165 CTD increases(expression) PTGS2 C432165 CTD increases(reaction) PTGS2 C432165 CTD decreases(reaction) PTGS2 C432165 CTD increases(expression) PTGS2 C432165 CTD increases(reaction) PTGS2 C432165 CTD decreases(reaction) PTX3 C432165 CTD increases(expression) PTX3 C432165 CTD decreases(expression) RAD51 C432165 CTD decreases(reaction) RAD51 C432165 CTD decreases(reaction) RB1 C432165 CTD increases(expression) RB1 C432165 CTD decreases(reaction) RELA C432165 CTD increases(activity) RELA C432165 CTD decreases(activity) RELA C432165 CTD decreases(reaction) RELA C432165 CTD decreases(reaction) RELA C432165 CTD increases(localization) RELA C432165 CTD affects(localization) RELA C432165 CTD decreases(reaction) RELA C432165 CTD decreases(activity) RPS6KB1 C432165 CTD decreases(reaction) RXRA C432165 CTD increases(phosphorylation) RXRA C432165 CTD increases(expression) SAA1 C432165 CTD increases(reaction) SAA1 C432165 CTD decreases(reaction) SCD C432165 CTD increases(expression) SCD C432165 CTD decreases(reaction) SERPINB2 C432165 CTD increases(expression) SERPINB2 C432165 CTD decreases(expression) SERPINE1 C432165 CTD decreases(reaction) SERPINE1 C432165 CTD decreases(activity) SGK1 C432165 CTD decreases(reaction) SOD2 C432165 CTD increases(expression) SOD2 C432165 CTD decreases(reaction) SOD2 C432165 CTD increases(expression) SOD2 C432165 CTD decreases(reaction) SREBF1 C432165 CTD increases(expression) SREBF1 C432165 CTD decreases(reaction) ST8SIA3 C432165 CTD increases(expression) ST8SIA3 C432165 CTD decreases(reaction) STAT3 C432165 CTD increases(phosphorylation) STAT3 C432165 CTD decreases(reaction) STAT3 C432165 CTD increases(phosphorylation) STAT3 C432165 CTD decreases(reaction) STAT3 C432165 CTD increases(activity) STAT3 C432165 CTD increases(phosphorylation) STAT3 C432165 CTD decreases(reaction) SULT1A1 C432165 CTD increases(expression) SULT1A1 C432165 CTD decreases(expression) TAT C432165 CTD decreases(reaction) TAT C432165 CTD affects(cotreatment) TERT C432165 CTD decreases(reaction) TERT C432165 CTD increases(expression) TERT C432165 CTD decreases(reaction) TGFB1 C432165 CTD decreases(response to substance) TGFB1 C432165 CTD increases(reaction) TGFB1 C432165 CTD decreases(reaction) TGFB1 C432165 CTD increases(expression) TGFB1 C432165 CTD increases(secretion) TGFB1 C432165 CTD affects(reaction) TNF C432165 CTD increases(expression) TNF C432165 CTD decreases(reaction) TNF C432165 CTD increases(secretion) TNF C432165 CTD increases(reaction) TNF C432165 CTD decreases(reaction) TNF C432165 CTD increases(expression) TNF C432165 CTD decreases(reaction) TNF C432165 CTD increases(secretion) TNF C432165 CTD affects(cotreatment) TNF C432165 CTD decreases(reaction) TNF C432165 CTD increases(expression) TNF C432165 CTD decreases(expression) TNF C432165 CTD decreases(reaction) TNF C432165 CTD decreases(reaction) TNF C432165 CTD increases(activity) TNF C432165 CTD decreases(reaction) TNF C432165 CTD increases(activity) TNF C432165 CTD increases(expression) TNF C432165 CTD decreases(reaction) TNF C432165 CTD increases(expression) TNF C432165 CTD decreases(reaction) TNF C432165 CTD increases(expression) TNF C432165 CTD increases(expression) TNF C432165 CTD decreases(reaction) TNF C432165 CTD increases(expression) TNF C432165 CTD increases(phosphorylation) TNF C432165 CTD affects(cotreatment) TNFRSF10B C432165 CTD decreases(reaction) TNFRSF10B C432165 CTD increases(expression) TNFRSF10B C432165 CTD decreases(reaction) TNFSF10 C432165 CTD increases(expression) TNFSF10 C432165 CTD affects(cotreatment) TNFSF10 C432165 CTD increases(cleavage) TNFSF10 C432165 CTD increases(response to substance) TNFSF10 C432165 CTD affects(binding) TOP1 C432165 CTD decreases(phosphorylation) TOP1 C432165 CTD decreases(reaction) TOP1 C432165 CTD decreases(reaction) TP53 C432165 CTD increases(activity) TP53 C432165 CTD increases(expression) TP53 C432165 CTD increases(phosphorylation) TP53 C432165 CTD decreases(reaction) TP53 C432165 CTD increases(expression) TP53 C432165 CTD decreases(reaction) TP53 C432165 CTD increases(phosphorylation) TP53 C432165 CTD decreases(expression) TP53 C432165 CTD increases(expression) TP53 C432165 CTD affects(reaction) TP53 C432165 CTD increases(expression) TP53 C432165 CTD affects(binding) TP53 C432165 CTD affects(cotreatment) TP53 C432165 CTD increases(reaction) TP53 C432165 CTD decreases(expression) TRHR C432165 CTD decreases(reaction) TRHR C432165 CTD decreases(reaction) UGT1A1 C432165 CTD increases(expression) UGT1A1 C432165 CTD decreases(reaction) VCAM1 C432165 CTD increases(expression) VCAM1 C432165 CTD decreases(reaction) VDR C432165 CTD increases(expression) VDR C432165 CTD decreases(reaction) VEGFA C432165 CTD decreases(secretion) VEGFA C432165 CTD decreases(reaction) VEGFA C432165 CTD increases(expression) VEGFA C432165 CTD decreases(reaction) VEGFA C432165 CTD increases(expression) VEGFA C432165 CTD decreases(expression) XIAP C432165 CTD decreases(reaction) XIAP C432165 PubChem Potency-Replicate_1 uM 29.849 AHR - GI(Protien) : PubChem Potency uM 3.162 ALDH1A1 - GI(Protien) : PubChem None uM CYP1A2 - GI(Protien) : PubChem None uM CYP1A2 - GI(Protien) : PubChem Potency uM 0.398 CYP2D6 - GI(Protien) : PubChem None uM CYP2D6 - GI(Protien) : PubChem Potency uM 3.981 CYP3A4 - GI(Protien) : PubChem None uM CYP3A4 - GI(Protien) : PubChem Potency uM 15.849 HIF1A - GI(Protien) : PubChem None uM IL1B - GI(Protien) : PubChem None uM KLK7 - GI(Protien) : PubChem None uM KLK7 - GI(Protien) : PubChem None uM MAP3K5 - GI(Protien) : PubChem Potency uM 10.000 MAPK1 - GI(Protien) : PubChem None uM MDM2 - GI(Protien) : PubChem None uM MDM4 - GI(Protien) : PubChem None uM NAE1 - GI(Protien) : PubChem None uM PABPC1 - GI(Protien) : PubChem None uM PIM1 - GI(Protien) : PubChem None uM PIM2 - GI(Protien) : PubChem Potency uM 31.623 POLB - GI(Protien) : PubChem None uM STK16 - GI(Protien) : PubChem Potency uM 5.957 TDP1 - GI(Protien) : PubChem Potency uM 6.684 TDP1 - GI(Protien) : PubChem Potency uM 8.912 TDP1 - GI(Protien) : PubChem Potency uM 10.000 TDP1 - GI(Protien) : PubChem Potency uM 21.136 TDP1 - GI(Protien) : PubChem None uM UBE2M - GI(Protien) : ChEMBL Potency nM 3162.300 ALDH1A1 - Target : CHEMBL3577 ChEMBL Inhibition - AURKB - Target : CHEMBL2185 ChEMBL Inhibition - CLK2 - Target : CHEMBL4225 ChEMBL AC50 nM 15.850 CYP1A2 - Target : CHEMBL3356 ChEMBL AC50 nM 398.110 CYP2D6 - Target : CHEMBL289 ChEMBL Potency nM 398.100 CYP2D6 - Target : CHEMBL289 ChEMBL AC50 nM 3981.070 CYP3A4 - Target : CHEMBL340 ChEMBL Potency nM 3981.100 CYP3A4 - Target : CHEMBL340 ChEMBL Inhibition - DAPK3 - Target : CHEMBL2468 ChEMBL Potency nM 15848.900 HIF1A - Target : CHEMBL4261 ChEMBL Potency nM 10000.000 MAPK1 - Target : CHEMBL4040 ChEMBL Inhibition - MAPK10 - Target : CHEMBL2637 ChEMBL Inhibition - PIM2 - Target : CHEMBL4523 ChEMBL Inhibition - PIM2 - Target : CHEMBL4523 ChEMBL Potency nM 31622.800 POLB - Target : CHEMBL2392 ChEMBL Inhibition - STK3 - Target : CHEMBL4708
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