Tan Lab | DSigDB

Gene Set: D4 : CTD - pyridaben

Collection

D4 : CTD

Chemical Name

pyridaben ( From PubChem : PYRIDABEN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
364.933 g/mol	0	4	5.2415	False(3/4)

Structure

InChI

InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3

InChIKey

DWFZBUWUXWZWKD-UHFFFAOYSA-N

Links

Gene (20 / 41)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(response to substance)			BCL2		C428725
CTD	decreases(reaction)			BCL2		C428725
CTD	increases(activity)			ESR1		C428725
CTD	decreases(reaction)			ODC1		C428725
CTD	increases(expression)			ODC1		C428725
CTD	increases(activity)			ODC1		C428725
CTD	affects(cotreatment)			PARP1		C428725
CTD	increases(cleavage)			PARP1		C428725
CTD	increases(response to substance)			SNCA		C428725
CTD	increases(activity)			VDR		C428725
PubChem	Potency-Replicate_1	uM	0.011	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	0.014	AR	-	GI(Protien) :
PubChem	None	uM		CHRM5	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	61.131	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.005	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	0.011	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.011	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	16.402	ESR1	-	GI(Protien) :
PubChem	IC50	uM	0.007	GALR3	-	GI(Protien) :
PubChem	IC50	uM	0.023	GALR3	-	GI(Protien) :
PubChem	None	uM		GALR3	-	GI(Protien) :
PubChem	None	uM		GALR3	-	GI(Protien) :
PubChem	None	uM		KCNQ1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.015	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	0.097	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	0.146	NFE2L2	-	GI(Protien) :
PubChem	EC50	uM		NOD1	-	GI(Protien) :
PubChem	EC50	uM		NOD2	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	IC50	uM	0.039	NR2F2	-	GI(Protien) :
PubChem	IC50	uM	0.062	NR2F2	-	GI(Protien) :
PubChem	None	uM		NR2F2	-	GI(Protien) :
PubChem	None	uM		NR2F2	-	GI(Protien) :
PubChem	None	uM		NR5A1	-	GI(Protien) :
PubChem	None	uM		NR5A2	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :
PubChem	Potency	uM	0.033	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.164	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	145.800	NFE2L2	-	Target : CHEMBL1075094

Download gene sets

gmt, text, Detailed text