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Gene Set: D4 : CTD - eplerenone

Collection D4 : CTD
Chemical Name eplerenone ( From PubChem : EPLERENONE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotApprovedNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
414.491 g/mol 0 6 3.1245 True
Structure
InChI InChI=1S/C24H30O6/c1-21-7-4-14(25)10-13(21)11-15(20(27)28-3)19-16-5-8-23(9-6-18(26)30-23)22(16,2)12-17-24(19,21)29-17/h10,15-17,19H,4-9,11-12H2,1-3H3/t15-,16+,17-,19+,21+,22+,23-,24-/m1/s1
InChIKey JUKPWJGBANNWMW-VWBFHTRKSA-N
Links

Gene (6 / 13)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDdecreases(reaction)ACTA2
C414690
CTDincreases(expression)ACTA2
C414690
CTDdecreases(expression)CDH1
C414690
CTDdecreases(reaction)CDH1
C414690
CTDdecreases(reaction)MAPK1
C414690
CTDincreases(activity)MAPK1
C414690
CTDincreases(phosphorylation)MAPK1
C414690
CTDdecreases(reaction)MAPK3
C414690
CTDincreases(activity)MAPK3
C414690
CTDincreases(phosphorylation)MAPK3
C414690
CTDdecreases(reaction)SNAI1
C414690
CTDincreases(expression)SNAI1
C414690
PubChem Ratio Potency (uM)uM11.100AR-GI(Protien) :
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