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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - 7,3'-dihydroxy-4'-methoxyisoflavone

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Collection	D4 : CTD
Chemical Name	7,3'-dihydroxy-4'-methoxyisoflavone ( From PubChem : CALYCOSIN )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 284.263 g/mol 2 5 2.8798 True
Structure
InChI	InChI=1S/C16H12O5/c1-20-14-5-2-9(6-13(14)18)12-8-21-15-7-10(17)3-4-11(15)16(12)19/h2-8,17-18H,1H3
InChIKey	ZZAJQOPSWWVMBI-UHFFFAOYSA-N
Links
Gene (39 / 44) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD increases(expression) ABHD14B C121707 CTD increases(expression) BLVRB C121707 CTD increases(expression) CCNB1 C121707 CTD decreases(expression) CCND3 C121707 CTD increases(expression) CCNG1 C121707 CTD increases(expression) CDK7 C121707 CTD decreases(expression) CDKN1A C121707 CTD decreases(expression) CDKN1C C121707 CTD decreases(expression) CDKN2D C121707 CTD increases(expression) EPO C121707 CTD increases(expression) ERP29 C121707 CTD decreases(degradation) HIF1A C121707 CTD increases(expression) HIF1A C121707 CTD decreases(expression) HMGB1 C121707 CTD increases(expression) KRT1 C121707 CTD increases(expression) LASP1 C121707 CTD increases(phosphorylation) MAPK1 C121707 CTD increases(phosphorylation) MAPK3 C121707 CTD decreases(expression) MCM5 C121707 CTD increases(expression) MCM6 C121707 CTD increases(expression) NME1 C121707 CTD increases(expression) PEBP1 C121707 CTD increases(expression) PGAM1 C121707 CTD increases(expression) PNPO C121707 CTD increases(expression) PRDX1 C121707 CTD decreases(expression) PRDX2 C121707 CTD decreases(expression) RAD9A C121707 CTD increases(expression) RBX1 C121707 CTD increases(expression) SKP1 C121707 CTD decreases(expression) SKP2 C121707 CTD increases(expression) STIP1 C121707 CTD increases(expression) TAGLN2 C121707 CTD increases(expression) UBE3A C121707 PubChem Potency uM 12.990 ATAD5 - GI(Protien) : PubChem Potency uM 12.589 BRCA1 - GI(Protien) : PubChem None uM GFER - GI(Protien) : PubChem None uM NR0B1 - GI(Protien) : PubChem None uM NR0B1 - GI(Protien) : PubChem None uM NR5A1 - GI(Protien) : PubChem Potency uM 25.119 POLB - GI(Protien) : PubChem None uM SMARCA2 - GI(Protien) : PubChem None uM SMARCA2 - GI(Protien) : ChEMBL Potency nM 12990.000 ATAD5 - Target : CHEMBL1741209 ChEMBL Potency nM 25118.900 POLB - Target : CHEMBL2392
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