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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - triethyl-(beta-4-stilbenoxyethyl)ammonium

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Collection	D4 : CTD
Chemical Name	triethyl-(beta-4-stilbenoxyethyl)ammonium ( From PubChem : STILONIUM IODIDE )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 451.384 g/mol 0 1 2.1163 True
Structure
InChI	InChI=1S/C22H30NO.HI/c1-4-23(5-2,6-3)18-19-24-22-16-14-21(15-17-22)13-12-20-10-8-7-9-11-20;/h7-17H,4-6,18-19H2,1-3H3;1H/q+1;/p-1/b13-12+;
InChIKey	RDTKUZXIHMTSJO-UEIGIMKUSA-M
Links
Gene (17 / 51) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(reaction) EGR1 C118602 CTD increases(secretion) EGR1 C118602 CTD affects(binding) EGR1 C118602 CTD increases(reaction) EGR1 C118602 CTD decreases(expression) EGR1 C118602 CTD increases(expression) EGR1 C118602 CTD decreases(reaction) FGF2 C118602 CTD increases(secretion) FGF2 C118602 CTD affects(binding) FGF2 C118602 CTD increases(reaction) FGF2 C118602 CTD affects(binding) FGF2 C118602 CTD decreases(expression) FGF2 C118602 CTD decreases(reaction) FGF2 C118602 CTD increases(reaction) FGF2 C118602 PubChem IC50_Mean uM 2.330 APOBEC3A - GI(Protien) : PubChem None uM APOBEC3A - GI(Protien) : PubChem None uM APOBEC3A - GI(Protien) : PubChem IC50 uM 2.570 APOBEC3G - GI(Protien) : PubChem Potency-Replicate_1 uM 10.591 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 13.448 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 16.785 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 18.996 AR - GI(Protien) : PubChem Ratio Potency (uM) uM 20.511 AR - GI(Protien) : PubChem Potency uM 56.234 BAZ2B - GI(Protien) : PubChem None uM CFTR - GI(Protien) : PubChem None uM CHRM1 - GI(Protien) : PubChem None uM CHRM4 - GI(Protien) : PubChem None uM CHRM5 - GI(Protien) : PubChem IC50 uM 20.224 CTDSP1 - GI(Protien) : PubChem None uM CTDSP1 - GI(Protien) : PubChem None uM CTDSP1 - GI(Protien) : PubChem Potency-Replicate_1 uM 29.849 CYP19A1 - GI(Protien) : PubChem None uM CYP19A1 - GI(Protien) : PubChem Potency-Replicate_1 uM 5.354 ESR1 - GI(Protien) : PubChem Ratio Potency (uM) uM 12.942 ESR1 - GI(Protien) : PubChem Ratio Potency (uM) uM 15.679 ESR1 - GI(Protien) : PubChem ER Potency (uM) uM 23.710 ESR1 - GI(Protien) : PubChem Potency-Replicate_1 uM 29.849 ESR1 - GI(Protien) : PubChem None uM MRGPRX1 - GI(Protien) : PubChem Ratio Potency (uM) uM 6.682 NFE2L2 - GI(Protien) : PubChem Potency uM 14.581 NFE2L2 - GI(Protien) : PubChem None uM PAX8 - GI(Protien) : PubChem Potency uM 2.593 TDP1 - GI(Protien) : PubChem Potency uM 3.663 TDP1 - GI(Protien) : PubChem Potency uM 4.217 TDP1 - GI(Protien) : PubChem Potency uM 4.611 TDP1 - GI(Protien) : PubChem Potency uM 5.309 TDP1 - GI(Protien) : ChEMBL IC50 nM 2330.000 APOBEC3A - Target : CHEMBL1741179 ChEMBL IC50 nM 2570.000 APOBEC3G - Target : CHEMBL1741217 ChEMBL Potency nM 56234.100 BAZ2B - Target : CHEMBL1741220 ChEMBL Potency nM 14581.000 NFE2L2 - Target : CHEMBL1075094
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