Tan Lab | DSigDB

Gene Set: D4 : CTD - 2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone

Collection

D4 : CTD

Chemical Name

2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone ( From PubChem : RH 1 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
234.251 g/mol	1	5	-0.8344	True

Structure

InChI

InChI=1S/C12H14N2O3/c1-7-9(13-2-3-13)12(17)8(6-15)10(11(7)16)14-4-5-14/h15H,2-6H2,1H3

InChIKey

Links

Gene (19 / 29)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(metabolic processing)			NQO1		C117776
CTD	increases(response to substance)			NQO1		C117776
CTD	increases(reduction)			NQO1		C117776
CTD	increases(activity)			NQO1		C117776
CTD	increases(reduction)			NQO1		C117776
CTD	increases(reduction)			POR		C117776
CTD	increases(activity)			POR		C117776
CTD	increases(reduction)			POR		C117776
PubChem	Potency	uM	2.668	ATXN2	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		EPAS1	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	None	uM		MITF	-	GI(Protien) :
PubChem	None	uM		NCOA1	-	GI(Protien) :
PubChem	None	uM		NCOA3	-	GI(Protien) :
PubChem	Potency	uM	0.517	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	1.636	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		OPRD1	-	GI(Protien) :
PubChem	None	uM		OPRM1	-	GI(Protien) :
PubChem	AC50_uM	uM	0.260	PAX8	-	GI(Protien) :
PubChem	None	uM		PAX8	-	GI(Protien) :
PubChem	None	uM		SENP8	-	GI(Protien) :
PubChem	Potency	uM	0.103	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.316	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.026	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.029	TDP1	-	GI(Protien) :
PubChem	None	uM		TNFRSF10B	-	GI(Protien) :

Download gene sets