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Gene Set: D4 : CTD - pimecrolimus

Collection D4 : CTD
Chemical Name pimecrolimus ( From PubChem : PIMECROLIMUS )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
810.453 g/mol 2 12 5.6573 False(1/4)
Structure
InChI InChI=1S/C43H68ClNO11/c1-10-30-18-24(2)17-25(3)19-36(53-8)39-37(54-9)21-27(5)43(51,56-39)40(48)41(49)45-16-12-11-13-32(45)42(50)55-38(28(6)33(46)23-34(30)47)26(4)20-29-14-15-31(44)35(22-29)52-7/h18,20,25,27-33,35-39,46,51H,10-17,19,21-23H2,1-9H3/t25-,27+,28+,29-,30+,31-,32?,33-,35+,36-,37-,38+,39?,43+/m0/s1
InChIKey KASDHRXLYQOAKZ-JQJNYORWSA-N
Links

Gene (7 / 9)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDdecreases(activity)ABCB11
C117268
CTDdecreases(expression)ICAM1
C117268
CTDdecreases(expression)IFNG
C117268
CTDdecreases(expression)IL2RA
C117268
CTDdecreases(expression)TNF
C117268
CTDdecreases(expression)TNFRSF4
C117268
PubChem Potency-Replicate_1uM3.349ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM10.682ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM22.555ESR1-GI(Protien) :
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