Tan Lab | DSigDB

Gene Set: D4 : CTD - difenoconazole

Collection

D4 : CTD

Chemical Name

difenoconazole ( From PubChem : DIFENOCONAZOLE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
406.263 g/mol	0	6	4.6655	True

Structure

InChI

InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3/t13-,19-/m1/s1

InChIKey

Links

Gene (12 / 18)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(expression)			AR		C115058
CTD	increases(expression)			FOLH1		C115058
CTD	decreases(expression)			KLK3		C115058
CTD	decreases(expression)			NKX3-1		C115058
CTD	decreases(expression)			PMEPA1		C115058
PubChem	Potency-Replicate_1	uM	13.685	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	15.355	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	30.638	CYP19A1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	11.296	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	13.685	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	1.933	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	2.009	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	15.355	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	44.668	NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	43.641	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	48.966	PPARD	-	GI(Protien) :
PubChem	Potency	uM	39.811	RXRA	-	GI(Protien) :

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