Tan Lab | DSigDB

Gene Set: D4 : CTD - eriodictyol

Collection

D4 : CTD

Chemical Name

eriodictyol ( From PubChem : ERIODICTYOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
288.252 g/mol	4	6	2.2155	True

Structure

InChI

InChI=1S/C15H12O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-5,13,16-19H,6H2/t13-/m0/s1

InChIKey

Links

Gene (19 / 28)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			ABCC1		C007619
CTD	decreases(activity)			GSTP1		C007619
CTD	increases(expression)			HMOX1		C007619
CTD	increases(expression)			NFE2L2		C007619
CTD	decreases(activity)			TBK1		C007619
PubChem	Potency	uM	10.000	ALOX15	-	GI(Protien) :
PubChem	EC50_Mean	uM	50.400	ALPI	-	GI(Protien) :
PubChem	None	uM		ALPI	-	GI(Protien) :
PubChem	EC50_Mean	uM	81.800	ALPL	-	GI(Protien) :
PubChem	EC50_Mean	uM	60.300	ALPPL2	-	GI(Protien) :
PubChem	Potency	uM	39.811	CYP3A4	-	GI(Protien) :
PubChem	None	uM		GFER	-	GI(Protien) :
PubChem	None	uM		GSTO1	-	GI(Protien) :
PubChem	Potency	uM	22.387	POLH	-	GI(Protien) :
PubChem	Potency	uM	75.686	POLH	-	GI(Protien) :
PubChem	Potency	uM	50.119	POLI	-	GI(Protien) :
PubChem	Potency	uM	15.849	POLK	-	GI(Protien) :
PubChem	Potency	uM	35.481	POLK	-	GI(Protien) :
PubChem	None	uM		PPP1CA	-	GI(Protien) :
PubChem	None	uM		PSIP1	-	GI(Protien) :
PubChem	None	uM		PSIP1	-	GI(Protien) :
ChEMBL	Potency	nM	10000.000	ALOX15	-	Target : CHEMBL2903
ChEMBL	EC50	nM	50400.000	ALPI	-	Target : CHEMBL5573
ChEMBL	EC50	nM	81800.000	ALPL	-	Target : CHEMBL5979
ChEMBL	EC50	nM	60300.000	ALPPL2	-	Target : CHEMBL3402
ChEMBL	Potency	nM	39810.700	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	79432.800	KDM4A	-	Target : CHEMBL5896
ChEMBL	Potency	nM	28183.800	KDM4E	-	Target : CHEMBL1293226

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