Tan Lab | DSigDB

Gene Set: D4 : CTD - finrozole

Collection

D4 : CTD

Chemical Name

finrozole ( From PubChem : 4-[3-(4-FLUOROPHENYL)-2-HYDROXY-1-(1H-1,2,4-TRIAZOL-1-YL)PROPYL]BENZONITRILE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
322.336 g/mol	1	5	2.48188	True

Structure

InChI

InChI=1S/C18H15FN4O/c19-16-7-3-13(4-8-16)9-17(24)18(23-12-21-11-22-23)15-5-1-14(10-20)2-6-15/h1-8,11-12,17-18,24H,9H2/t17-,18-/m1/s1

InChIKey

Links

Gene (9 / 24)

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Source	Type	Gene	Other
CTD	affects(cotreatment)	ABCB4	C111409
CTD	increases(expression)	ABCB4	C111409
CTD	affects(cotreatment)	ABCC2	C111409
CTD	decreases(expression)	ABCC2	C111409
CTD	increases(expression)	ABCC2	C111409
CTD	decreases(reaction)	ABCC2	C111409
CTD	affects(cotreatment)	ABCG2	C111409
CTD	decreases(expression)	ABCG2	C111409
CTD	increases(expression)	ABCG2	C111409
CTD	decreases(reaction)	CYP19A1	C111409
CTD	increases(expression)	CYP19A1	C111409
CTD	decreases(chemical synthesis)	CYP19A1	C111409
CTD	decreases(reaction)	CYP19A1	C111409
CTD	increases(expression)	CYP19A1	C111409
CTD	decreases(reaction)	CYP1A1	C111409
CTD	increases(expression)	CYP1A1	C111409
CTD	decreases(reaction)	FSHB	C111409
CTD	increases(secretion)	FSHB	C111409
CTD	decreases(reaction)	HSD17B1	C111409
CTD	increases(expression)	HSD17B1	C111409
CTD	decreases(reaction)	HSD3B1	C111409
CTD	increases(expression)	HSD3B1	C111409
CTD	decreases(reaction)	SLC22A11	C111409
CTD	increases(expression)	SLC22A11	C111409

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