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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - methyl-beta-cyclodextrin

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Collection	D4 : CTD
Chemical Name	methyl-beta-cyclodextrin ( From PubChem : TRIMETHYL-BETA-CYCLODEXTRIN )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 1429.54 g/mol 0 35 -1.4945 False(2/4)
Structure
InChI	InChI=1S/C63H112O35/c1-64-22-29-36-43(71-8)50(78-15)57(85-29)93-37-30(23-65-2)87-59(52(80-17)44(37)72-9)95-39-32(25-67-4)89-61(54(82-19)46(39)74-11)97-41-34(27-69-6)91-63(56(84-21)48(41)76-13)98-42-35(28-70-7)90-62(55(83-20)49(42)77-14)96-40-33(26-68-5)88-60(53(81-18)47(40)75-12)94-38-31(24-66-3)86-58(92-36)51(79-16)45(38)73-10/h29-63H,22-28H2,1-21H3/t29-,30-,31-,32-,33-,34-,35-,36?,37?,38?,39?,40?,41?,42?,43+,44+,45+,46+,47+,48+,49+,50-,51-,52-,53-,54-,55-,56-,57?,58?,59?,60?,61?,62?,63?/m1/s1
InChIKey	DSDAICPXUXPBCC-SUXUVDNMSA-N
Links
Gene (19 / 41) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(reaction) CASP3 C108732 CTD increases(cleavage) CASP3 C108732 CTD decreases(reaction) CASP6 C108732 CTD increases(cleavage) CASP6 C108732 CTD decreases(reaction) CASR C108732 CTD increases(uptake) CASR C108732 CTD decreases(abundance) CXCL8 C108732 CTD decreases(reaction) CXCL8 C108732 CTD increases(expression) CXCL8 C108732 CTD decreases(reaction) ICAM1 C108732 CTD increases(expression) ICAM1 C108732 CTD decreases(reaction) JAK1 C108732 CTD increases(phosphorylation) JAK1 C108732 CTD decreases(reaction) MAPK1 C108732 CTD increases(phosphorylation) MAPK1 C108732 CTD decreases(reaction) MAPK3 C108732 CTD increases(phosphorylation) MAPK3 C108732 CTD decreases(reaction) PARP1 C108732 CTD increases(cleavage) PARP1 C108732 CTD decreases(reaction) PRKCD C108732 CTD increases(localization) PRKCD C108732 CTD affects(localization) RELA C108732 CTD decreases(abundance) RELA C108732 CTD decreases(reaction) RELA C108732 CTD affects(localization) SLC31A1 C108732 CTD decreases(reaction) SLC31A1 C108732 CTD decreases(reaction) SLC39A4 C108732 CTD increases(degradation) SLC39A4 C108732 CTD decreases(reaction) SRC C108732 CTD increases(phosphorylation) SRC C108732 CTD affects(localization) TF C108732 CTD affects(localization) TNF C108732 CTD decreases(abundance) TNF C108732 CTD decreases(reaction) TNF C108732 CTD increases(expression) TNF C108732 CTD decreases(reaction) TNFRSF10B C108732 CTD increases(expression) TNFRSF10B C108732 CTD decreases(reaction) VCAM1 C108732 CTD increases(expression) VCAM1 C108732 CTD decreases(reaction) VDR C108732 CTD increases(expression) VDR C108732
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