Tan Lab | DSigDB

Gene Set: D4 : CTD - fludioxonil

Collection

D4 : CTD

Chemical Name

fludioxonil ( From PubChem : FLUDIOXONIL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
248.185 g/mol	1	3	2.87488	True

Structure

InChI

InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H

InChIKey

MUJOIMFVNIBMKC-UHFFFAOYSA-N

Links

Gene (25 / 65)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			AHR		C108339
CTD	increases(activity)			AHR		C108339
CTD	affects(binding)			AR		C108339
CTD	decreases(reaction)			AR		C108339
CTD	increases(expression)			AR		C108339
CTD	decreases(expression)			BCL2		C108339
CTD	increases(expression)			BCL2		C108339
CTD	decreases(reaction)			BCL2		C108339
CTD	increases(expression)			CASP3		C108339
CTD	affects(cotreatment)			CASP3		C108339
CTD	affects(reaction)			CCND1		C108339
CTD	decreases(expression)			CCND1		C108339
CTD	decreases(reaction)			CCND1		C108339
CTD	increases(expression)			CCND1		C108339
CTD	affects(reaction)			ESR1		C108339
CTD	decreases(expression)			ESR1		C108339
CTD	affects(binding)			ESR1		C108339
CTD	increases(activity)			ESR1		C108339
CTD	affects(cotreatment)			ESR1		C108339
CTD	decreases(expression)			ESR1		C108339
CTD	increases(activity)			ESR1		C108339
CTD	decreases(reaction)			ESR2		C108339
CTD	increases(expression)			ESR2		C108339
CTD	decreases(expression)			ESR2		C108339
CTD	increases(expression)			GPX1		C108339
CTD	affects(cotreatment)			GPX1		C108339
CTD	affects(cotreatment)			H2AFX		C108339
CTD	increases(phosphorylation)			H2AFX		C108339
CTD	increases(expression)			MIR200A		C108339
CTD	decreases(reaction)			MIR21		C108339
CTD	increases(expression)			MIR21		C108339
CTD	decreases(expression)			MIR21		C108339
CTD	decreases(expression)			MIR22		C108339
CTD	increases(expression)			NRF1		C108339
CTD	increases(expression)			PARP1		C108339
CTD	decreases(expression)			PDCD4		C108339
CTD	decreases(reaction)			PDCD4		C108339
CTD	decreases(reaction)			PGR		C108339
CTD	increases(expression)			PGR		C108339
CTD	decreases(expression)			PGR		C108339
CTD	decreases(expression)			PTEN		C108339
CTD	decreases(expression)			RARB		C108339
CTD	increases(activity)			RXRB		C108339
CTD	affects(cotreatment)			VMP1		C108339
CTD	decreases(expression)			VMP1		C108339
PubChem	AhR Potency (uM)	uM	6.352	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	12.197	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	12.300	AR	-	GI(Protien) :
PubChem	Potency	uM	17.783	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	29.484	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	30.638	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	27.306	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	10.965	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	13.801	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	13.801	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	17.374	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	40.080	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	48.558	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	19.494	NR1H4	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	9.770	NR3C1	-	GI(Protien) :
PubChem	Potency	uM	31.623	PPARG	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :
PubChem	Potency	uM	2.239	RXRA	-	GI(Protien) :

Download gene sets

gmt, text, Detailed text