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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - 6-(methylamino)pyrido(3,4-d)pyrimidine

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Collection	D4 : CTD
Chemical Name	6-(methylamino)pyrido(3,4-d)pyrimidine ( From PubChem : PD 158780 )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 330.183 g/mol 2 4 3.7186 True
Structure
InChI	InChI=1S/C14H12BrN5/c1-16-13-6-11-12(7-17-13)18-8-19-14(11)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20)
InChIKey	KFHMLBXBRCITHF-UHFFFAOYSA-N
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Gene (11 / 11) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(secretion) AREG C107875 CTD decreases(activity) CDK2 C107875 CTD increases(expression) CDKN1B C107875 CTD decreases(activity) EGFR C107875 CTD decreases(activity) ERBB2 C107875 CTD decreases(activity) ERBB3 C107875 CTD decreases(activity) ERBB4 C107875 CTD decreases(phosphorylation) RB1 C107875 CTD decreases(expression) RBL1 C107875 CTD increases(expression) RBL2 C107875 PubChem None uM GAPDH - GI(Protien) :
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