Tan Lab | DSigDB

Gene Set: D4 : CTD - N-(4-hydroxyphenyl)arachidonylamide

Collection

D4 : CTD

Chemical Name

N-(4-hydroxyphenyl)arachidonylamide ( From PubChem : AM 404 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
395.577 g/mol	2	3	7.5494	False(3/4)

Structure

InChI

InChI=1S/C26H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-26(29)27-24-20-22-25(28)23-21-24/h6-7,9-10,12-13,15-16,20-23,28H,2-5,8,11,14,17-19H2,1H3,(H,27,29)/b7-6-,10-9-,13-12-,16-15-

InChIKey

IJBZOOZRAXHERC-DOFZRALJSA-N

Links

Gene (12 / 29)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			NFATC2		C107594
CTD	affects(cotreatment)			TNF		C107594
CTD	decreases(reaction)			TNF		C107594
CTD	increases(expression)			TNF		C107594
CTD	decreases(expression)			TNF		C107594
CTD	decreases(secretion)			TNF		C107594
CTD	affects(binding)			TRPV1		C107594
CTD	decreases(reaction)			TRPV1		C107594
CTD	increases(activity)			TRPV1		C107594
PubChem	Potency	uM	0.251	ALOX15	-	GI(Protien) :
PubChem	IC50	uM		CACNA1B	-	GI(Protien) :
PubChem	Potency	uM	5.012	CYP2C9	-	GI(Protien) :
PubChem	None	uM		CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	5.012	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	31.623	GAA	-	GI(Protien) :
PubChem	Potency	uM	35.481	HPGD	-	GI(Protien) :
PubChem	None	uM		MAPT	-	GI(Protien) :
PubChem	None	uM		PLA2G7	-	GI(Protien) :
PubChem	Potency	uM	21.136	TDP1	-	GI(Protien) :
PubChem	Potency	uM	26.609	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	251.200	ALOX15	-	Target : CHEMBL2903
ChEMBL	AC50	nM	5011.870	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	5011.900	CYP2C9	-	Target : CHEMBL3397
ChEMBL	AC50	nM	5011.870	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	5011.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	31622.800	GAA	-	Target : CHEMBL2608
ChEMBL	Potency	nM	35481.300	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	14125.400	MAPT	-	Target : CHEMBL1293224

Download gene sets

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