Tan Lab | DSigDB

Gene Set: D4 : CTD - abacavir

Collection

D4 : CTD

Chemical Name

abacavir ( From PubChem : ABACAVIR )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
286.332 g/mol	3	7	1.7465	True

Structure

InChI

InChI=1S/C14H18N6O/c15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21/h1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19)/t8-,10+/m1/s1

InChIKey

Links

Gene (18 / 27)

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Source	Type	Unit	Gene	PMID	Other
CTD	affects(binding)		ADH1A		C106538
CTD	increases(metabolic processing)		ADH1A		C106538
CTD	affects(binding)		ALB		C106538
CTD	affects(binding)		ALB		C106538
CTD	decreases(reaction)		ALB		C106538
CTD	increases(expression)		CRP		C106538
CTD	increases(expression)		GFAP		C106538
CTD	increases(response to substance)		HLA-B		C106538
CTD	affects(response to substance)		HLA-B		C106538
CTD	increases(response to substance)		HLA-B		C106538
CTD	increases(secretion)		HLA-B		C106538
CTD	affects(binding)		HLA-C		C106538
CTD	increases(response to substance)		IFNG		C106538
CTD	increases(secretion)		IFNG		C106538
CTD	increases(response to substance)		IL13		C106538
CTD	increases(secretion)		IL13		C106538
CTD	affects(response to substance)		IL4		C106538
CTD	increases(expression)		MMP9		C106538
CTD	increases(expression)		MPO		C106538
CTD	increases(expression)		SYP		C106538
CTD	decreases(activity)		TERT		C106538
CTD	increases(response to substance)		TNF		C106538
CTD	increases(secretion)		TNF		C106538
CTD	increases(expression)		UCP1		C106538
ChEMBL	Activity	-	ABCC1	-	Target : CHEMBL3004
ChEMBL	Activity	-	ABCC2	-	Target : CHEMBL5748
ChEMBL	Activity	-	ABCC3	-	Target : CHEMBL5918

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