Tan Lab | DSigDB

Gene Set: D4 : CTD - fraxetin

Collection

D4 : CTD

Chemical Name

fraxetin ( From PubChem : FRAXETIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
208.168 g/mol	2	5	1.2128	True

Structure

InChI

InChI=1S/C10H8O5/c1-14-6-4-5-2-3-7(11)15-10(5)9(13)8(6)12/h2-4,12-13H,1H3

InChIKey

Links

Gene (13 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			BAX		C105671
CTD	decreases(activity)			CASP3		C105671
CTD	decreases(activity)			CASP9		C105671
CTD	decreases(reaction)			CAT		C105671
CTD	increases(activity)			CAT		C105671
CTD	increases(expression)			CAT		C105671
CTD	affects(localization)			CYCS		C105671
CTD	decreases(reaction)			SOD2		C105671
CTD	increases(activity)			SOD2		C105671
CTD	increases(expression)			SOD2		C105671
PubChem	Potency	uM	12.589	ALOX15	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	8.912	FEN1	-	GI(Protien) :
PubChem	Potency	uM	7.943	POLK	-	GI(Protien) :
PubChem	Potency	uM	50.119	POLK	-	GI(Protien) :
PubChem	Potency	uM	20.596	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	12589.300	ALOX15	-	Target : CHEMBL2903
ChEMBL	Potency	nM	7943.300	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	794.300	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	1584.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	6309.600	KDM4A	-	Target : CHEMBL5896

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