Tan Lab | DSigDB

Gene Set: D4 : CTD - xanthohumol

Collection

D4 : CTD

Chemical Name

xanthohumol ( From PubChem : XANTHOHUMOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
354.396 g/mol	3	5	4.2168	True

Structure

InChI

InChI=1S/C21H22O5/c1-13(2)4-10-16-18(24)12-19(26-3)20(21(16)25)17(23)11-7-14-5-8-15(22)9-6-14/h4-9,11-12,22,24-25H,10H2,1-3H3/b11-7+

InChIKey

ORXQGKIUCDPEAJ-YRNVUSSQSA-N

Links

Gene (34 / 60)

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Source	Type	Unit	Gene	PMID	Other
CTD	affects(binding)		ABCC5		C104536
CTD	decreases(activity)		ABCC5		C104536
CTD	decreases(export)		ABCC5		C104536
CTD	decreases(reaction)		ABCC5		C104536
CTD	increases(export)		ABCC5		C104536
CTD	increases(activity)		ALPL		C104536
CTD	increases(expression)		ALPL		C104536
CTD	decreases(expression)		BCL2		C104536
CTD	increases(activity)		CASP3		C104536
CTD	increases(cleavage)		CASP3		C104536
CTD	increases(activity)		CASP7		C104536
CTD	increases(cleavage)		CASP7		C104536
CTD	increases(activity)		CASP8		C104536
CTD	increases(cleavage)		CASP8		C104536
CTD	increases(activity)		CASP9		C104536
CTD	increases(cleavage)		CASP9		C104536
CTD	decreases(reaction)		CFTR		C104536
CTD	increases(export)		CFTR		C104536
CTD	increases(expression)		CYP1A1		C104536
CTD	increases(reaction)		CYP1A1		C104536
CTD	decreases(activity)		CYP1A1		C104536
CTD	decreases(reaction)		CYP1A2		C104536
CTD	increases(expression)		CYP1A2		C104536
CTD	affects(cotreatment)		GSTA1		C104536
CTD	increases(expression)		GSTA1		C104536
CTD	decreases(expression)		GSTA1		C104536
CTD	increases(expression)		GSTP1		C104536
CTD	increases(expression)		GSTT1		C104536
CTD	increases(expression)		HMOX1		C104536
CTD	decreases(expression)		ICAM1		C104536
CTD	decreases(expression)		IL6		C104536
CTD	decreases(activity)		MMP9		C104536
CTD	decreases(expression)		MMP9		C104536
CTD	decreases(activity)		MYL2		C104536
CTD	decreases(phosphorylation)		MYL2		C104536
CTD	affects(cotreatment)		NAT2		C104536
CTD	increases(expression)		NAT2		C104536
CTD	affects(localization)		NFE2L2		C104536
CTD	increases(activity)		NFE2L2		C104536
CTD	increases(expression)		NFE2L2		C104536
CTD	increases(expression)		NQO1		C104536
CTD	increases(cleavage)		PARP1		C104536
CTD	decreases(activity)		PTGS2		C104536
CTD	decreases(expression)		PXN		C104536
CTD	decreases(expression)		S100A4		C104536
CTD	decreases(reaction)		SELE		C104536
CTD	increases(expression)		SELE		C104536
CTD	decreases(expression)		SULT1A1		C104536
CTD	increases(expression)		SULT1A1		C104536
CTD	increases(expression)		TFF1		C104536
CTD	decreases(reaction)		TNF		C104536
CTD	increases(expression)		TNF		C104536
CTD	increases(expression)		TP53		C104536
CTD	increases(expression)		UGT1A1		C104536
CTD	increases(reaction)		UGT1A1		C104536
CTD	increases(expression)		VWF		C104536
ChEMBL	Activity	-	MAPK1	-	Target : CHEMBL1907606
ChEMBL	Activity	-	MAPK1	-	Target : CHEMBL1907606
ChEMBL	Activity	-	MAPK3	-	Target : CHEMBL1907606
ChEMBL	Activity	-	MAPK3	-	Target : CHEMBL1907606

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