Tan Lab | DSigDB

Gene Set: D4 : CTD - harmol

Collection

D4 : CTD

Chemical Name

harmol ( From PubChem : HARMOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
198.221 g/mol	2	1	2.3178	True

Structure

InChI

InChI=1S/C12H10N2O/c1-7-12-10(4-5-13-7)9-3-2-8(15)6-11(9)14-12/h2-6,13-14H,1H3

InChIKey

Links

Gene (18 / 33)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			CYP1A1		C001326
CTD	decreases(stability)			CYP1A1		C001326
CTD	increases(expression)			CYP1A1		C001326
CTD	decreases(activity)			CYP1A1		C001326
CTD	decreases(reaction)			SULT1A1		C001326
CTD	increases(sulfation)			SULT1A1		C001326
CTD	increases(sulfation)			SULT1A3		C001326
PubChem	None	uM		AHR	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	15.849	CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	50.119	EHMT2	-	GI(Protien) :
PubChem	None	uM		EPAS1	-	GI(Protien) :
PubChem	None	uM		HIF1A	-	GI(Protien) :
PubChem	None	uM		NCF1	-	GI(Protien) :
PubChem	None	uM		NCOA1	-	GI(Protien) :
PubChem	None	uM		NCOA3	-	GI(Protien) :
PubChem	IC50	uM	44.910	RACGAP1	-	GI(Protien) :
PubChem	AC50_uM	uM	23.890	RAD54L	-	GI(Protien) :
PubChem	None	uM		RAD54L	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
PubChem	Potency	uM	14.581	TDP1	-	GI(Protien) :
PubChem	Potency	uM	20.596	TDP1	-	GI(Protien) :
PubChem	Potency	uM	23.715	TDP1	-	GI(Protien) :
PubChem	Potency	uM	25.119	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	8.200	TDP1	-	GI(Protien) :
PubChem	Potency	uM	12.995	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	15848.900	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	50118.700	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	25118.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	25118.900	HSD17B10	-	Target : CHEMBL4159

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