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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - perfluoro-n-nonanoic acid

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Collection	D4 : CTD
Chemical Name	perfluoro-n-nonanoic acid ( From PubChem : PERFLUORONONANOIC ACID )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 464.076 g/mol 1 2 5.0804 False(3/4)
Structure
InChI	InChI=1S/C9HF17O2/c10-2(11,1(27)28)3(12,13)4(14,15)5(16,17)6(18,19)7(20,21)8(22,23)9(24,25)26/h(H,27,28)
InChIKey	UZUFPBIDKMEQEQ-UHFFFAOYSA-N
Links
Gene (29 / 38) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD increases(expression) ABCB4 C101816 CTD increases(expression) ACOX1 C101816 CTD increases(expression) ACSL1 C101816 CTD decreases(expression) ACTB C101816 CTD increases(expression) ALAS1 C101816 CTD increases(expression) ANGPTL4 C101816 CTD increases(expression) APOA2 C101816 CTD increases(expression) APOA5 C101816 CTD increases(expression) CPT1A C101816 CTD increases(expression) CYP2B6 C101816 CTD increases(expression) CYP4A11 C101816 CTD decreases(expression) CYP7A1 C101816 CTD increases(expression) DDIT3 C101816 CTD affects(binding) ESR1 C101816 CTD increases(activity) ESR1 C101816 CTD increases(expression) FABP1 C101816 CTD increases(expression) HADHA C101816 CTD decreases(expression) HMGCR C101816 CTD increases(expression) HMGCS2 C101816 CTD increases(expression) PDK4 C101816 CTD increases(expression) PLIN2 C101816 CTD increases(expression) POR C101816 CTD increases(expression) PPARD C101816 CTD increases(expression) SCD C101816 CTD decreases(reaction) SLC22A11 C101816 CTD increases(import) SLC22A11 C101816 CTD affects(cotreatment) SLC22A12 C101816 CTD decreases(reaction) SLC22A12 C101816 CTD increases(import) SLC22A12 C101816 CTD increases(expression) TXNIP C101816 PubChem Ratio Potency (uM) uM 19.494 ESR1 - GI(Protien) : PubChem Potency-Replicate_1 uM 27.536 ESR1 - GI(Protien) : PubChem Potency-Replicate_1 uM 6.859 NFE2L2 - GI(Protien) : PubChem Ratio Potency (uM) uM 13.685 NFE2L2 - GI(Protien) : PubChem Potency uM 24.337 NFE2L2 - GI(Protien) : PubChem None uM PPARG - GI(Protien) : PubChem Potency uM 125.893 THRB - GI(Protien) : ChEMBL Potency nM 125892.000 THRB - Target : CHEMBL1947
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