Tan Lab | DSigDB

Gene Set: D4 : CTD - azaribine

Collection

D4 : CTD

Chemical Name

azaribine ( From PubChem : AZARIBINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
371.299 g/mol	1	11	-1.7445	False(3/4)

Structure

InChI

InChI=1S/C14H17N3O9/c1-6(18)23-5-9-11(24-7(2)19)12(25-8(3)20)13(26-9)17-14(22)16-10(21)4-15-17/h4,9,11-13H,5H2,1-3H3,(H,16,21,22)/t9-,11-,12-,13-/m1/s1

InChIKey

QQOBRRFOVWGIMD-OJAKKHQRSA-N

Links

Gene (13 / 18)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(activity)			UMPS		C100231
PubChem	Potency-Replicate_1	uM	5.354	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	2.683	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	3.510	ESR1	-	GI(Protien) :
PubChem	None	uM		JAK2	-	GI(Protien) :
PubChem	None	uM		JAK2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	None	uM		PPARD	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.841	PPARG	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :
PubChem	Potency	uM	10.000	SMN2	-	GI(Protien) :
PubChem	None	uM		STAT1	-	GI(Protien) :
PubChem	Potency	uM	10.593	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	10000.000	SMN1; SMN2	-	Target : CHEMBL1293232

Download gene sets

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