Tan Lab | DSigDB

Gene Set: D4 : CTD - prostaglandin A2

Collection

D4 : CTD

Chemical Name

prostaglandin A2 ( From PubChem : 8-ISO PROSTAGLANDIN A2 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
334.45 g/mol	2	4	4.0563	True

Structure

InChI

InChI=1S/C20H30O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h4,7,12-18,21H,2-3,5-6,8-11H2,1H3,(H,23,24)/b7-4+,14-12+/t16-,17-,18+/m1/s1

InChIKey

MYHXHCUNDDAEOZ-GZJGQNSBSA-N

Links

Gene (18 / 25)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(metabolic processing)			GSTA1		C100008
CTD	affects(metabolic processing)			GSTA2		C100008
CTD	affects(metabolic processing)			GSTM1		C100008
CTD	increases(abundance)			TNF		C100008
PubChem	Potency	uM	39.811	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	50.119	BAZ2B	-	GI(Protien) :
PubChem	None	uM		CDC25B	-	GI(Protien) :
PubChem	None	uM		DUSP1	-	GI(Protien) :
PubChem	Potency	uM	35.481	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	22.387	HPGD	-	GI(Protien) :
PubChem	None	uM		ITGA4	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	IC50	uM		PABPC1	-	GI(Protien) :
PubChem	Potency	uM	3.162	POLB	-	GI(Protien) :
PubChem	None	uM		PTBP1	-	GI(Protien) :
PubChem	None	uM		PTGER2	-	GI(Protien) :
PubChem	None	uM		PTPN22	-	GI(Protien) :
PubChem	None	uM		PTPN22	-	GI(Protien) :
PubChem	IC50	uM	13.700	PTPN7	-	GI(Protien) :
ChEMBL	Potency	nM	39810.700	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	50118.700	BAZ2B	-	Target : CHEMBL1741220
ChEMBL	Potency	nM	35481.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	22387.200	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	3162.300	POLB	-	Target : CHEMBL2392
ChEMBL	IC50	nM	13700.000	PTPN7	-	Target : CHEMBL2219

Download gene sets

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