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Gene Set: D4 : CTD - azaspirane

Collection D4 : CTD
Chemical Name azaspirane ( From PubChem : ATIPRIMOD )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
336.598 g/mol 0 2 5.5089 False(3/4)
Structure
InChI InChI=1S/C22H44N2/c1-5-10-21(11-6-2)12-14-22(15-13-21)16-19-24(20-22)18-9-17-23(7-3)8-4/h5-20H2,1-4H3
InChIKey SERHTTSLBVGRBY-UHFFFAOYSA-N
Links

Gene (10 / 18)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDincreases(activity)CASP3
C099015
CTDincreases(cleavage)CASP3
C099015
CTDincreases(activity)CASP8
C099015
CTDincreases(cleavage)CASP8
C099015
CTDdecreases(reaction)IL6
C099015
CTDincreases(phosphorylation)IL6
C099015
CTDdecreases(reaction)JAK2
C099015
CTDincreases(phosphorylation)JAK2
C099015
CTDdecreases(expression)MCL1
C099015
CTDdecreases(reaction)NFKBIA
C099015
CTDincreases(phosphorylation)NFKBIA
C099015
CTDincreases(cleavage)PARP1
C099015
CTDdecreases(reaction)RELA
C099015
CTDincreases(phosphorylation)RELA
C099015
CTDdecreases(reaction)STAT3
C099015
CTDincreases(phosphorylation)STAT3
C099015
CTDdecreases(reaction)TNF
C099015
CTDincreases(phosphorylation)TNF
C099015
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