Tan Lab | DSigDB

Gene Set: D4 : CTD - tenofovir

Collection

D4 : CTD

Chemical Name

tenofovir ( From PubChem : 9-(2-PHOSPHONOMETHOXYPROPYL)ADENINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
287.212 g/mol	3	9	0.53	True

Structure

InChI

InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m1/s1

InChIKey

Links

Gene (14 / 21)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
CTD	increases(expression)		BNIP3L		C096918
CTD	increases(expression)		CCL20		C096918
CTD	increases(secretion)		CCL20		C096918
CTD	decreases(expression)		COX2		C096918
CTD	increases(reaction)		COX2		C096918
CTD	increases(expression)		CXCL8		C096918
CTD	increases(secretion)		CXCL8		C096918
CTD	decreases(activity)		CYP2C9		C096918
CTD	decreases(reaction)		EDN1		C096918
CTD	increases(secretion)		EDN1		C096918
CTD	decreases(phosphorylation)		NOS3		C096918
CTD	decreases(reaction)		NOS3		C096918
CTD	increases(expression)		NT5E		C096918
CTD	decreases(expression)		NT5M		C096918
CTD	decreases(reaction)		SLC22A6		C096918
CTD	increases(response to substance)		SLC22A6		C096918
CTD	increases(uptake)		SLC22A6		C096918
CTD	decreases(expression)		TNF		C096918
ChEMBL	Activity	-	ABCC1	-	Target : CHEMBL3004
ChEMBL	Activity	-	ABCC2	-	Target : CHEMBL5748
ChEMBL	Activity	-	ABCC3	-	Target : CHEMBL5918

Download gene sets