Tan Lab | DSigDB

Gene Set: D4 : CTD - aripiprazole

Collection

D4 : CTD

Chemical Name

aripiprazole ( From PubChem : ARIPIPRAZOLE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
448.385 g/mol	1	5	5.0002	False(3/4)

Structure

InChI

InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)

InChIKey

CEUORZQYGODEFX-UHFFFAOYSA-N

Links

Gene (22 / 50)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			CES1		C094645
CTD	increases(hydrolysis)			CES1		C094645
CTD	affects(binding)			DRD2		C094645
CTD	increases(activity)			DRD2		C094645
CTD	affects(activity)			HTR1A		C094645
CTD	affects(binding)			HTR1A		C094645
CTD	affects(binding)			HTR1A		C094645
CTD	increases(activity)			HTR1A		C094645
CTD	affects(binding)			HTR2A		C094645
CTD	decreases(activity)			HTR2A		C094645
CTD	affects(binding)			HTR2A		C094645
CTD	increases(activity)			HTR2A		C094645
CTD	decreases(reaction)			HTR2A		C094645
CTD	decreases(response to substance)			HTR2A		C094645
CTD	affects(response to substance)			HTR2A		C094645
CTD	affects(activity)			HTR2C		C094645
CTD	affects(binding)			HTR2C		C094645
CTD	decreases(reaction)			KCNH2		C094645
CTD	increases(transport)			KCNH2		C094645
CTD	decreases(reaction)			PRL		C094645
CTD	increases(expression)			PRL		C094645
CTD	decreases(reaction)			PRL		C094645
CTD	increases(secretion)			PRL		C094645
CTD	decreases(expression)			PRL		C094645
CTD	affects(binding)			SLC6A4		C094645
PubChem	None	uM		APAF1	-	GI(Protien) :
PubChem	None	uM		DRD1	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		GNA15	-	GI(Protien) :
PubChem	None	uM		GNA15	-	GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		MAP3K3	-	GI(Protien) :
PubChem	None	uM		MAP4K2	-	GI(Protien) :
PubChem	None	uM		MAP4K2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		PLA2G7	-	GI(Protien) :
PubChem	None	uM		PLA2G7	-	GI(Protien) :
PubChem	None	uM		RGS4	-	GI(Protien) :
PubChem	None	uM		RGS4	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
PubChem	Potency	uM	14.581	TDP1	-	GI(Protien) :
PubChem	Potency	uM	16.360	TDP1	-	GI(Protien) :

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