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Gene Set: D4 : CTD - pirfenidone

Collection D4 : CTD
Chemical Name pirfenidone ( From PubChem : PIRFENIDONE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedApprovedNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
185.222 g/mol 0 2 2.1459 True
Structure
InChI InChI=1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3
InChIKey ISWRGOKTTBVCFA-UHFFFAOYSA-N
Links

Gene (5 / 14)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDdecreases(reaction)ESR1
C093844
CTDincreases(phosphorylation)ESR1
C093844
CTDdecreases(response to substance)ESR1
C093844
CTDdecreases(reaction)JUN
C093844
CTDincreases(expression)JUN
C093844
CTDdecreases(response to substance)JUN
C093844
CTDdecreases(reaction)MAPK12
C093844
CTDincreases(expression)MAPK12
C093844
CTDdecreases(response to substance)MAPK12
C093844
CTDincreases(phosphorylation)MAPK12
C093844
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
ChEMBLAC50nM31622.800CYP1A2
-Target : CHEMBL3356
ChEMBLPotencynM31622.800HSD17B10
-Target : CHEMBL4159
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