DSigDB

Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - spermine nitric oxide complex

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Collection	D4 : CTD
Chemical Name	spermine nitric oxide complex ( From PubChem : SPERMINE NONOATE )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 262.352 g/mol 4 8 1.4349 True
Structure
InChI	InChI=1S/C10H26N6O2/c11-5-3-8-13-7-1-2-9-15(10-4-6-12)16(18)14-17/h13,18H,1-12H2
InChIKey	QPIOUFBAROSIAN-UHFFFAOYSA-N
Links
Gene (8 / 19) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD increases(expression) ANXA5 C091861 CTD affects(localization) CYCS C091861 CTD decreases(reaction) FASLG C091861 CTD increases(abundance) FASLG C091861 CTD increases(activity) FASLG C091861 CTD decreases(reaction) NOS3 C091861 CTD increases(abundance) NOS3 C091861 CTD increases(metabolic processing) NOS3 C091861 CTD decreases(activity) NOS3 C091861 CTD increases(cleavage) PARP1 C091861 CTD decreases(reaction) SOD1 C091861 CTD increases(abundance) SOD1 C091861 CTD increases(metabolic processing) SOD1 C091861 CTD decreases(activity) SOD1 C091861 CTD decreases(reaction) TP53 C091861 CTD increases(phosphorylation) TP53 C091861 CTD affects(response to substance) TP53 C091861 PubChem Potency uM 13.336 TDP1 - GI(Protien) : PubChem Potency uM 13.336 TDP1 - GI(Protien) :
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