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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - 1-((4-methylsulfonyl)phenyl)-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole

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Collection	D4 : CTD
Chemical Name	1-((4-methylsulfonyl)phenyl)-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole ( From PubChem : SC-58125 )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 384.348 g/mol 0 4 5.1815 False(3/4)
Structure
InChI	InChI=1S/C17H12F4N2O2S/c1-26(24,25)14-8-6-13(7-9-14)23-15(10-16(22-23)17(19,20)21)11-2-4-12(18)5-3-11/h2-10H,1H3
InChIKey	JHBIMJKLBUMNAU-UHFFFAOYSA-N
Links
Gene (8 / 11) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD increases(expression) ATF3 C090859 CTD increases(expression) ATF3 C090859 CTD decreases(activity) CYP19A1 C090859 CTD decreases(expression) CYP19A1 C090859 CTD decreases(reaction) IL1B C090859 CTD increases(chemical synthesis) IL1B C090859 CTD increases(expression) PAWR C090859 CTD decreases(activity) PTGS1 C090859 CTD decreases(activity) PTGS2 C090859 CTD increases(expression) TNFRSF10A C090859 CTD increases(expression) TNFRSF10B C090859
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