Tan Lab | DSigDB

Gene Set: D4 : CTD - olomoucine

Collection

D4 : CTD

Chemical Name

olomoucine ( From PubChem : OLOMOUCINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
298.343 g/mol	3	7	1.5256	True

Structure

InChI

InChI=1S/C15H18N6O/c1-21-10-18-12-13(17-9-11-5-3-2-4-6-11)19-15(16-7-8-22)20-14(12)21/h2-6,10,22H,7-9H2,1H3,(H2,16,17,19,20)

InChIKey

Links

Gene (8 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(phosphorylation)			CDK1		C090046
CTD	decreases(reaction)			CDK1		C090046
CTD	increases(reaction)			CDK1		C090046
CTD	decreases(reaction)			CDK2		C090046
CTD	increases(phosphorylation)			CDK2		C090046
CTD	increases(expression)			RB1		C090046
CTD	increases(expression)			SP1		C090046
CTD	decreases(phosphorylation)			TP53		C090046
CTD	decreases(reaction)			TP53		C090046
CTD	increases(reaction)			TP53		C090046
CTD	decreases(reaction)			TPI1		C090046
CTD	increases(phosphorylation)			TPI1		C090046
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	1.259	CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	3.162	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
ChEMBL	AC50	nM	5011.870	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	1258.930	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	3162.300	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	1258.900	CYP2D6	-	Target : CHEMBL289

Download gene sets