Tan Lab | DSigDB

Gene Set: D4 : CTD - 4-biphenylamine

Collection

D4 : CTD

Chemical Name

4-biphenylamine ( From PubChem : 4-AMINOBIPHENYL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
169.222 g/mol	1	1	3.517	True

Structure

InChI

InChI=1S/C12H11N/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9H,13H2

InChIKey

DMVOXQPQNTYEKQ-UHFFFAOYSA-N

Links

Gene (90 / 109)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			ALB		C006757
CTD	decreases(expression)			BRCA1		C006757
CTD	decreases(expression)			CHEK1		C006757
CTD	decreases(expression)			CIDEA		C006757
CTD	affects(metabolic processing)			CYP1A2		C006757
CTD	increases(activity)			CYP1A2		C006757
CTD	increases(activity)			CYP1A2		C006757
CTD	increases(hydroxylation)			CYP1A2		C006757
CTD	decreases(activity)			CYP1A2		C006757
CTD	decreases(response to substance)			CYP1A2		C006757
CTD	increases(activity)			CYP2A13		C006757
CTD	increases(hydroxylation)			CYP2A13		C006757
CTD	increases(reduction)			CYP2S1		C006757
CTD	increases(expression)			DDIT3		C006757
CTD	decreases(expression)			EXO1		C006757
CTD	decreases(expression)			FANCG		C006757
CTD	decreases(expression)			FEN1		C006757
CTD	increases(expression)			GADD45G		C006757
CTD	affects(cotreatment)			HIST3H3		C006757
CTD	decreases(methylation)			HIST3H3		C006757
CTD	increases(mutagenesis)			HPRT1		C006757
CTD	increases(response to substance)			HPRT1		C006757
CTD	decreases(expression)			IP6K3		C006757
CTD	affects(cotreatment)			KDM1A		C006757
CTD	affects(localization)			KDM1A		C006757
CTD	decreases(expression)			LIG1		C006757
CTD	increases(expression)			MIR1181		C006757
CTD	increases(expression)			MIR1183		C006757
CTD	increases(expression)			MIR1202		C006757
CTD	increases(expression)			MIR1228		C006757
CTD	increases(expression)			MIR1234		C006757
CTD	increases(expression)			MIR1238		C006757
CTD	increases(expression)			MIR1246		C006757
CTD	increases(expression)			MIR1268A		C006757
CTD	increases(expression)			MIR1287		C006757
CTD	increases(expression)			MIR1290		C006757
CTD	increases(expression)			MIR1305		C006757
CTD	increases(expression)			MIR15A		C006757
CTD	increases(expression)			MIR17		C006757
CTD	increases(expression)			MIR18A		C006757
CTD	increases(expression)			MIR18B		C006757
CTD	increases(expression)			MIR1914		C006757
CTD	increases(expression)			MIR1915		C006757
CTD	increases(expression)			MIR1973		C006757
CTD	increases(expression)			MIR20B		C006757
CTD	increases(expression)			MIR21		C006757
CTD	increases(expression)			MIR22		C006757
CTD	increases(expression)			MIR29A		C006757
CTD	increases(expression)			MIR320A		C006757
CTD	increases(expression)			MIR340		C006757
CTD	increases(expression)			MIR372		C006757
CTD	increases(expression)			MIR378A		C006757
CTD	increases(expression)			MIR421		C006757
CTD	increases(expression)			MIR425		C006757
CTD	increases(expression)			MIR431		C006757
CTD	increases(expression)			MIR452		C006757
CTD	increases(expression)			MIR454		C006757
CTD	increases(expression)			MIR494		C006757
CTD	increases(expression)			MIR500A		C006757
CTD	increases(expression)			MIR545		C006757
CTD	increases(expression)			MIR572		C006757
CTD	increases(expression)			MIR574		C006757
CTD	increases(expression)			MIR575		C006757
CTD	increases(expression)			MIR630		C006757
CTD	increases(expression)			MIR638		C006757
CTD	increases(expression)			MIR660		C006757
CTD	increases(expression)			MIR663A		C006757
CTD	increases(expression)			MIR7-1		C006757
CTD	increases(expression)			MIR744		C006757
CTD	increases(expression)			MIR762		C006757
CTD	increases(expression)			MIR874		C006757
CTD	increases(expression)			MIR887		C006757
CTD	increases(expression)			MIR93		C006757
CTD	increases(expression)			MIR939		C006757
CTD	increases(expression)			MIR940		C006757
CTD	increases(expression)			MIRLET7B		C006757
CTD	affects(metabolic processing)			MPO		C006757
CTD	decreases(expression)			MSH2		C006757
CTD	affects(response to substance)			NAT1		C006757
CTD	increases(response to substance)			NAT1		C006757
CTD	increases(mutagenesis)			NAT1		C006757
CTD	increases(acetylation)			NAT1		C006757
CTD	increases(response to substance)			NAT1		C006757
CTD	increases(acetylation)			NAT1		C006757
CTD	increases(activity)			NAT1		C006757
CTD	increases(acetylation)			NAT2		C006757
CTD	increases(activity)			NAT2		C006757
CTD	decreases(expression)			OGG1		C006757
CTD	decreases(expression)			PCNA		C006757
CTD	increases(metabolic processing)			PTGS1		C006757
CTD	increases(metabolic processing)			PTGS2		C006757
CTD	decreases(expression)			RAD18		C006757
CTD	decreases(expression)			RAD51		C006757
CTD	decreases(expression)			RPA1		C006757
CTD	decreases(reaction)			SULT1A1		C006757
CTD	increases(sulfation)			SULT1A1		C006757
CTD	affects(binding)			TP53		C006757
CTD	affects(response to substance)			TP53		C006757
CTD	decreases(expression)			TP73		C006757
CTD	decreases(expression)			TREX1		C006757
CTD	increases(glucuronidation)			UGT1A4		C006757
CTD	increases(glucuronidation)			UGT1A9		C006757
CTD	decreases(expression)			UNG		C006757
CTD	decreases(expression)			XRCC2		C006757
CTD	decreases(expression)			XRCC3		C006757
PubChem	AhR Potency (uM)	uM	31.481	AHR	-	GI(Protien) :
PubChem	Potency	uM	12.589	CYP3A4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.025	ESR1	-	GI(Protien) :
ChEMBL	Potency	nM	12589.300	CYP3A4	-	Target : CHEMBL340

Download gene sets

gmt, text, Detailed text