Tan Lab | DSigDB

Gene Set: D4 : CTD - pentabromodiphenyl ether

Collection

D4 : CTD

Chemical Name

pentabromodiphenyl ether ( From PubChem : PENTABROMODIPHENYL ETHER )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
564.688 g/mol	0	1	7.2914	False(2/4)

Structure

InChI

InChI=1S/C12H5Br5O/c13-6-1-2-11(9(16)3-6)18-12-5-8(15)7(14)4-10(12)17/h1-5H

InChIKey

WHPVYXDFIXRKLN-UHFFFAOYSA-N

Links

Gene (415 / 428)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			ABCB9		C086401
CTD	increases(expression)			ACBD3		C086401
CTD	increases(expression)			ADPRM		C086401
CTD	decreases(expression)			ADRA2A		C086401
CTD	increases(expression)			AHCYL1		C086401
CTD	increases(expression)			AHR		C086401
CTD	increases(expression)			AHSA2		C086401
CTD	increases(expression)			AKAP17A		C086401
CTD	increases(expression)			ALDH8A1		C086401
CTD	increases(expression)			AOC2		C086401
CTD	increases(expression)			APOE		C086401
CTD	decreases(expression)			AQP11		C086401
CTD	decreases(reaction)			AR		C086401
CTD	increases(activity)			AR		C086401
CTD	increases(expression)			ARG2		C086401
CTD	decreases(expression)			ARHGAP11A		C086401
CTD	decreases(expression)			ARHGEF39		C086401
CTD	increases(expression)			ARHGEF7		C086401
CTD	increases(expression)			ARL5B		C086401
CTD	decreases(expression)			ARSB		C086401
CTD	decreases(expression)			ASB4		C086401
CTD	increases(expression)			ASNS		C086401
CTD	increases(expression)			ATF3		C086401
CTD	increases(expression)			ATL2		C086401
CTD	decreases(expression)			ATPAF1		C086401
CTD	decreases(expression)			B4GALT5		C086401
CTD	increases(expression)			BAG2		C086401
CTD	affects(localization)			BAX		C086401
CTD	increases(expression)			BCL10		C086401
CTD	increases(expression)			BHLHE40		C086401
CTD	increases(expression)			BHLHE41		C086401
CTD	increases(expression)			BIRC3		C086401
CTD	decreases(expression)			BLOC1S1		C086401
CTD	increases(expression)			BLOC1S3		C086401
CTD	increases(expression)			BLZF1		C086401
CTD	decreases(expression)			BMP2K		C086401
CTD	increases(expression)			BNIP1		C086401
CTD	decreases(expression)			BRD7		C086401
CTD	decreases(expression)			BRI3BP		C086401
CTD	increases(expression)			C10ORF88		C086401
CTD	decreases(expression)			C11ORF87		C086401
CTD	decreases(expression)			C14ORF37		C086401
CTD	increases(expression)			C16ORF72		C086401
CTD	increases(expression)			C17ORF51		C086401
CTD	increases(expression)			C18ORF25		C086401
CTD	increases(expression)			C1ORF54		C086401
CTD	increases(expression)			C1QTNF1		C086401
CTD	increases(expression)			C6ORF48		C086401
CTD	increases(expression)			C9ORF72		C086401
CTD	decreases(expression)			CACNA1G		C086401
CTD	decreases(expression)			CALM3		C086401
CTD	increases(expression)			CALML4		C086401
CTD	increases(expression)			CARD18		C086401
CTD	decreases(expression)			CARD6		C086401
CTD	increases(activity)			CASP3		C086401
CTD	increases(activity)			CASP8		C086401
CTD	increases(activity)			CASP9		C086401
CTD	increases(expression)			CCBL1		C086401
CTD	increases(expression)			CCDC170		C086401
CTD	increases(expression)			CCNB1IP1		C086401
CTD	decreases(expression)			CCNF		C086401
CTD	increases(expression)			CCNL1		C086401
CTD	increases(expression)			CCNO		C086401
CTD	increases(expression)			CCNT1		C086401
CTD	increases(expression)			CCT6P1		C086401
CTD	decreases(expression)			CD59		C086401
CTD	decreases(expression)			CD83		C086401
CTD	decreases(expression)			CDC25C		C086401
CTD	decreases(expression)			CDH11		C086401
CTD	decreases(expression)			CDKN2B		C086401
CTD	increases(expression)			CDR2		C086401
CTD	increases(expression)			CEBPD		C086401
CTD	increases(expression)			CEBPG		C086401
CTD	decreases(expression)			CEMIP		C086401
CTD	increases(expression)			CEP83		C086401
CTD	increases(expression)			CHAC1		C086401
CTD	increases(expression)			CHST7		C086401
CTD	increases(expression)			CIRBP		C086401
CTD	increases(expression)			CITED2		C086401
CTD	increases(expression)			CLEC4A		C086401
CTD	increases(expression)			CLK1		C086401
CTD	increases(expression)			CLK3		C086401
CTD	increases(expression)			CLK4		C086401
CTD	increases(expression)			COL8A2		C086401
CTD	increases(expression)			CPEB2		C086401
CTD	increases(expression)			CPEB4		C086401
CTD	increases(expression)			CREBRF		C086401
CTD	increases(expression)			CREBZF		C086401
CTD	increases(expression)			CSNK1A1		C086401
CTD	decreases(expression)			CTSC		C086401
CTD	increases(expression)			CTTN		C086401
CTD	increases(expression)			CXADR		C086401
CTD	decreases(reaction)			CXCL8		C086401
CTD	increases(expression)			CXCL8		C086401
CTD	decreases(expression)			CXCR4		C086401
CTD	increases(expression)			CYP1A2		C086401
CTD	increases(expression)			CYP1B1		C086401
CTD	increases(expression)			CYP3A4		C086401
CTD	increases(expression)			CYR61		C086401
CTD	increases(expression)			DDIT3		C086401
CTD	increases(expression)			DDX17		C086401
CTD	increases(expression)			DENND5B		C086401
CTD	increases(expression)			DFNB31		C086401
CTD	decreases(expression)			DHCR24		C086401
CTD	decreases(expression)			DHFRL1		C086401
CTD	increases(expression)			DIO1		C086401
CTD	decreases(expression)			DKK1		C086401
CTD	increases(expression)			DNAJB9		C086401
CTD	decreases(expression)			DOLK		C086401
CTD	decreases(expression)			DPY19L1		C086401
CTD	decreases(expression)			DTNA		C086401
CTD	increases(expression)			DUSP4		C086401
CTD	decreases(expression)			EFNA3		C086401
CTD	increases(phosphorylation)			EGFR		C086401
CTD	increases(expression)			EGR1		C086401
CTD	increases(expression)			EIF2AK3		C086401
CTD	increases(expression)			EIF3B		C086401
CTD	decreases(expression)			ELAC1		C086401
CTD	decreases(expression)			ELP6		C086401
CTD	increases(expression)			EPB41L4A-AS1		C086401
CTD	increases(expression)			ERC2		C086401
CTD	increases(expression)			ETV5		C086401
CTD	decreases(expression)			F2R		C086401
CTD	decreases(expression)			FAM173B		C086401
CTD	decreases(expression)			FAM69A		C086401
CTD	increases(expression)			FAM76B		C086401
CTD	increases(expression)			FAM98A		C086401
CTD	decreases(expression)			FASTKD5		C086401
CTD	increases(expression)			FBN2		C086401
CTD	increases(expression)			FBXO45		C086401
CTD	increases(expression)			FEM1B		C086401
CTD	increases(expression)			FHL2		C086401
CTD	decreases(expression)			FITM2		C086401
CTD	increases(expression)			FKBP11		C086401
CTD	increases(expression)			FNIP1		C086401
CTD	increases(expression)			FOSL2		C086401
CTD	decreases(expression)			FOXE1		C086401
CTD	increases(expression)			FOXO3		C086401
CTD	increases(expression)			FSD1L		C086401
CTD	increases(expression)			FUS		C086401
CTD	decreases(expression)			FZD1		C086401
CTD	increases(expression)			FZD10		C086401
CTD	increases(expression)			GADD45A		C086401
CTD	decreases(expression)			GALNT4		C086401
CTD	increases(expression)			GAS5		C086401
CTD	decreases(expression)			GATM		C086401
CTD	increases(expression)			GFPT1		C086401
CTD	increases(expression)			GMPPB		C086401
CTD	increases(expression)			GOLGA4		C086401
CTD	increases(expression)			GOLPH3L		C086401
CTD	increases(expression)			GOSR2		C086401
CTD	increases(expression)			GPC4		C086401
CTD	decreases(expression)			GPR183		C086401
CTD	decreases(expression)			GPR22		C086401
CTD	decreases(expression)			GPR61		C086401
CTD	decreases(expression)			GPRC5A		C086401
CTD	increases(expression)			GSTM1		C086401
CTD	increases(expression)			GUCA1B		C086401
CTD	increases(expression)			GUSBP1		C086401
CTD	increases(expression)			HBP1		C086401
CTD	decreases(expression)			HDAC1		C086401
CTD	decreases(expression)			HDAC8		C086401
CTD	increases(expression)			HK2		C086401
CTD	increases(expression)			HLF		C086401
CTD	decreases(expression)			HOXA11-AS		C086401
CTD	increases(expression)			HS3ST3A1		C086401
CTD	decreases(expression)			HSPA2		C086401
CTD	increases(expression)			HSPA5		C086401
CTD	increases(expression)			HSPBAP1		C086401
CTD	increases(expression)			HSPD1		C086401
CTD	increases(expression)			ICAM1		C086401
CTD	increases(expression)			IFRD1		C086401
CTD	decreases(reaction)			IL6		C086401
CTD	increases(expression)			IL6		C086401
CTD	increases(expression)			IRF2BP2		C086401
CTD	decreases(activity)			IYD		C086401
CTD	decreases(expression)			JMJD4		C086401
CTD	increases(expression)			JMJD6		C086401
CTD	increases(expression)			JMY		C086401
CTD	decreases(expression)			KCNB1		C086401
CTD	decreases(expression)			KCTD1		C086401
CTD	increases(expression)			KDELR2		C086401
CTD	decreases(expression)			KIAA1161		C086401
CTD	decreases(expression)			KIAA2022		C086401
CTD	decreases(expression)			KIF1B		C086401
CTD	increases(expression)			KLF9		C086401
CTD	increases(expression)			KLHL24		C086401
CTD	increases(expression)			KLHL28		C086401
CTD	increases(expression)			LARP1B		C086401
CTD	increases(expression)			LATS2		C086401
CTD	increases(expression)			LCORL		C086401
CTD	increases(expression)			LEAP2		C086401
CTD	increases(expression)			LINC00115		C086401
CTD	decreases(expression)			LMNB1		C086401
CTD	decreases(expression)			LNPEP		C086401
CTD	increases(expression)			LPP		C086401
CTD	increases(expression)			MAFF		C086401
CTD	increases(expression)			MALAT1		C086401
CTD	decreases(expression)			MAN2C1		C086401
CTD	decreases(expression)			MARCKSL1		C086401
CTD	increases(expression)			MARS		C086401
CTD	decreases(expression)			MAT2A		C086401
CTD	increases(expression)			MBNL2		C086401
CTD	increases(expression)			MCEE		C086401
CTD	increases(expression)			MCTP2		C086401
CTD	decreases(expression)			MED13		C086401
CTD	increases(expression)			MEF2D		C086401
CTD	decreases(expression)			MEG3		C086401
CTD	increases(expression)			MPHOSPH8		C086401
CTD	increases(expression)			MRPL39		C086401
CTD	increases(expression)			MTHFD1L		C086401
CTD	increases(expression)			MTSS1		C086401
CTD	increases(expression)			MX1		C086401
CTD	increases(expression)			MXD1		C086401
CTD	increases(expression)			MYL6		C086401
CTD	increases(expression)			N4BP2L2		C086401
CTD	decreases(expression)			NAP1L2		C086401
CTD	decreases(expression)			NAT1		C086401
CTD	decreases(expression)			NCOA5		C086401
CTD	decreases(expression)			NDP		C086401
CTD	increases(expression)			NEAT1		C086401
CTD	increases(expression)			NFIL3		C086401
CTD	increases(expression)			NFKBIB		C086401
CTD	increases(expression)			NFXL1		C086401
CTD	increases(expression)			NHSL1		C086401
CTD	decreases(expression)			NOTCH3		C086401
CTD	increases(expression)			NPR3		C086401
CTD	increases(expression)			NR1H4		C086401
CTD	increases(activity)			NR1I2		C086401
CTD	increases(expression)			NR4A1		C086401
CTD	increases(expression)			NR4A2		C086401
CTD	decreases(expression)			NRGN		C086401
CTD	decreases(expression)			NT5DC2		C086401
CTD	decreases(expression)			NTAN1		C086401
CTD	increases(expression)			NUPL1		C086401
CTD	increases(expression)			OCIAD1		C086401
CTD	decreases(expression)			OGFRL1		C086401
CTD	increases(expression)			OR7D2		C086401
CTD	increases(expression)			PACRGL		C086401
CTD	increases(expression)			PARD3		C086401
CTD	decreases(expression)			PCDH18		C086401
CTD	decreases(expression)			PCTP		C086401
CTD	increases(expression)			PDCD5		C086401
CTD	decreases(expression)			PDK2		C086401
CTD	decreases(expression)			PDK3		C086401
CTD	increases(expression)			PDXDC1		C086401
CTD	increases(expression)			PER1		C086401
CTD	increases(expression)			PGM2L1		C086401
CTD	increases(expression)			PGM3		C086401
CTD	increases(expression)			PHC3		C086401
CTD	decreases(expression)			PHTF1		C086401
CTD	decreases(expression)			PIAS2		C086401
CTD	increases(expression)			PIM1		C086401
CTD	increases(expression)			PLD6		C086401
CTD	increases(expression)			PPP1R15A		C086401
CTD	decreases(expression)			PPP2R1B		C086401
CTD	decreases(expression)			PRDM2		C086401
CTD	affects(localization)			PRKCA		C086401
CTD	affects(localization)			PRKCE		C086401
CTD	affects(localization)			PRKCZ		C086401
CTD	decreases(expression)			PROS1		C086401
CTD	increases(expression)			PROX1		C086401
CTD	increases(expression)			PRPSAP1		C086401
CTD	increases(expression)			PRRC1		C086401
CTD	decreases(expression)			PRRT3		C086401
CTD	decreases(expression)			PRSS35		C086401
CTD	increases(expression)			PSMA3		C086401
CTD	decreases(expression)			PTGR1		C086401
CTD	increases(expression)			PTP4A1		C086401
CTD	decreases(expression)			RAB15		C086401
CTD	increases(expression)			RABGGTB		C086401
CTD	increases(expression)			RAPGEF4		C086401
CTD	increases(expression)			RASSF1		C086401
CTD	decreases(expression)			RBM12		C086401
CTD	increases(expression)			RBM15		C086401
CTD	increases(expression)			RBM26		C086401
CTD	increases(expression)			RBM33		C086401
CTD	decreases(expression)			RCAN3		C086401
CTD	increases(expression)			RND3		C086401
CTD	increases(expression)			RNF113A		C086401
CTD	decreases(expression)			RNF170		C086401
CTD	increases(expression)			RORA		C086401
CTD	increases(expression)			RPL31		C086401
CTD	increases(expression)			RPL37		C086401
CTD	increases(expression)			RSBN1		C086401
CTD	increases(expression)			RSRC2		C086401
CTD	increases(expression)			RSRP1		C086401
CTD	increases(expression)			SARNP		C086401
CTD	increases(expression)			SARS		C086401
CTD	increases(expression)			SDE2		C086401
CTD	increases(expression)			SEC24A		C086401
CTD	increases(expression)			SERAC1		C086401
CTD	affects(binding)			SERPINA7		C086401
CTD	increases(expression)			SESN2		C086401
CTD	decreases(expression)			SETMAR		C086401
CTD	increases(expression)			SFXN3		C086401
CTD	increases(expression)			SGCD		C086401
CTD	increases(expression)			SHMT2		C086401
CTD	decreases(expression)			SLC16A10		C086401
CTD	increases(expression)			SLC22A15		C086401
CTD	decreases(expression)			SLC25A1		C086401
CTD	increases(expression)			SLC25A25		C086401
CTD	decreases(expression)			SLC27A4		C086401
CTD	increases(expression)			SLC3A2		C086401
CTD	decreases(expression)			SLC40A1		C086401
CTD	decreases(expression)			SLC4A8		C086401
CTD	increases(expression)			SLC7A11		C086401
CTD	decreases(reaction)			SLCO1B1		C086401
CTD	increases(import)			SLCO1B1		C086401
CTD	decreases(reaction)			SLCO1B3		C086401
CTD	increases(import)			SLCO1B3		C086401
CTD	decreases(reaction)			SLCO2B1		C086401
CTD	increases(import)			SLCO2B1		C086401
CTD	increases(expression)			SMIM7		C086401
CTD	increases(expression)			SNHG1		C086401
CTD	increases(expression)			SNHG10		C086401
CTD	increases(expression)			SNHG12		C086401
CTD	increases(expression)			SNHG8		C086401
CTD	increases(expression)			SNRPA1		C086401
CTD	increases(expression)			SOX30		C086401
CTD	decreases(expression)			SPC24		C086401
CTD	increases(expression)			SPRY2		C086401
CTD	decreases(expression)			SREBF1		C086401
CTD	decreases(expression)			SRGAP1		C086401
CTD	increases(expression)			SRP54		C086401
CTD	increases(expression)			ST3GAL1		C086401
CTD	decreases(expression)			ST8SIA4		C086401
CTD	increases(expression)			STX3		C086401
CTD	increases(expression)			SYNE1		C086401
CTD	increases(expression)			TAF1D		C086401
CTD	increases(expression)			TANC2		C086401
CTD	increases(expression)			TARDBP		C086401
CTD	increases(expression)			TBC1D22A		C086401
CTD	increases(expression)			TBL2		C086401
CTD	increases(expression)			TBRG1		C086401
CTD	decreases(expression)			TBRG4		C086401
CTD	increases(expression)			TDH		C086401
CTD	decreases(expression)			TESC		C086401
CTD	decreases(expression)			TFDP1		C086401
CTD	affects(binding)			THRA		C086401
CTD	decreases(reaction)			THRA		C086401
CTD	affects(binding)			THRB		C086401
CTD	decreases(reaction)			THRB		C086401
CTD	increases(expression)			TICAM2		C086401
CTD	increases(expression)			TIPARP		C086401
CTD	increases(expression)			TLN1		C086401
CTD	decreases(expression)			TMEM165		C086401
CTD	decreases(expression)			TMEM19		C086401
CTD	decreases(expression)			TMEM2		C086401
CTD	increases(expression)			TMEM39A		C086401
CTD	increases(expression)			TMEM50B		C086401
CTD	decreases(expression)			TMEM51		C086401
CTD	increases(expression)			TNFSF13B		C086401
CTD	decreases(expression)			TNRC18		C086401
CTD	decreases(expression)			TOMM40L		C086401
CTD	decreases(expression)			TOR1AIP2		C086401
CTD	increases(expression)			TP53		C086401
CTD	decreases(expression)			TRAM1L1		C086401
CTD	increases(expression)			TRIB1		C086401
CTD	increases(expression)			TRIB3		C086401
CTD	increases(expression)			TRNAU1AP		C086401
CTD	decreases(expression)			TSEN2		C086401
CTD	decreases(expression)			TSHZ3		C086401
CTD	increases(expression)			TTBK2		C086401
CTD	decreases(expression)			TTC30B		C086401
CTD	decreases(expression)			TTPAL		C086401
CTD	affects(binding)			TTR		C086401
CTD	increases(expression)			TXN		C086401
CTD	increases(expression)			TXN2		C086401
CTD	decreases(expression)			TXNIP		C086401
CTD	decreases(expression)			TXNIP		C086401
CTD	decreases(expression)			TXNRD2		C086401
CTD	increases(expression)			U2AF1L4		C086401
CTD	increases(expression)			UAP1L1		C086401
CTD	increases(expression)			UFM1		C086401
CTD	increases(expression)			UHRF2		C086401
CTD	increases(expression)			URB1		C086401
CTD	decreases(expression)			UTP23		C086401
CTD	increases(expression)			VCPKMT		C086401
CTD	decreases(expression)			VSTM4		C086401
CTD	increases(expression)			WHSC1L1		C086401
CTD	increases(expression)			WRNIP1		C086401
CTD	increases(expression)			XBP1		C086401
CTD	increases(expression)			XRN1		C086401
CTD	increases(expression)			YARS		C086401
CTD	increases(expression)			YRDC		C086401
CTD	increases(expression)			ZBTB10		C086401
CTD	increases(expression)			ZBTB2		C086401
CTD	increases(expression)			ZBTB21		C086401
CTD	increases(expression)			ZBTB43		C086401
CTD	decreases(expression)			ZC3H10		C086401
CTD	decreases(expression)			ZDHHC12		C086401
CTD	increases(expression)			ZFAND2A		C086401
CTD	increases(expression)			ZNF133		C086401
CTD	increases(expression)			ZNF24		C086401
CTD	increases(expression)			ZNF26		C086401
CTD	increases(expression)			ZNF277		C086401
CTD	increases(expression)			ZNF280B		C086401
CTD	decreases(expression)			ZNF341		C086401
CTD	decreases(expression)			ZNF37A		C086401
CTD	increases(expression)			ZNF396		C086401
CTD	increases(expression)			ZNF432		C086401
CTD	decreases(expression)			ZNF451		C086401
CTD	decreases(expression)			ZNF488		C086401
CTD	increases(expression)			ZNF550		C086401
CTD	decreases(expression)			ZNF551		C086401
CTD	decreases(expression)			ZNF559		C086401
CTD	decreases(expression)			ZNF594		C086401
CTD	increases(expression)			ZNF595		C086401
CTD	decreases(expression)			ZNF681		C086401
CTD	decreases(expression)			ZNF708		C086401
CTD	decreases(expression)			ZNF709		C086401
CTD	decreases(expression)			ZNF780A		C086401
CTD	decreases(expression)			ZNF780B		C086401
CTD	decreases(expression)			ZNF83		C086401
CTD	increases(expression)			ZNF836		C086401
CTD	decreases(expression)			ZNF91		C086401
CTD	decreases(expression)			ZNRF1		C086401
CTD	increases(expression)			ZRSR1		C086401
CTD	increases(expression)			ZSCAN18		C086401
CTD	increases(expression)			ZXDC		C086401
PubChem	None	uM		ABL1	-	GI(Protien) :
PubChem	None	uM		ABL1	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	13.012	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	61.566	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	39.811	NR1I2	-	GI(Protien) :
PubChem	None	uM		RIN1	-	GI(Protien) :
PubChem	None	uM		RIN1	-	GI(Protien) :

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