DSigDB Home
Search Gene
Collections
Browse Gene Sets
Download
Help

Gene Set: D4 : CTD - baicalein

Collection D4 : CTD
Chemical Name baicalein ( From PubChem : BAICALEIN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
270.237 g/mol 3 5 2.5768 True
Structure
InChI InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H
InChIKey FXNFHKRTJBSTCS-UHFFFAOYSA-N
Links

Gene (72 / 168)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDdecreases(activity)ABCC1
C006680
CTDaffects(reaction)AHR
C006680
CTDdecreases(phosphorylation)AHR
C006680
CTDaffects(response to substance)AHR
C006680
CTDaffects(binding)AHR
C006680
CTDincreases(activity)AHR
C006680
CTDincreases(expression)AHR
C006680
CTDdecreases(phosphorylation)AKT1
C006680
CTDdecreases(reaction)AKT1
C006680
CTDdecreases(reaction)ALOX12
C006680
CTDincreases(chemical synthesis)ALOX12
C006680
CTDdecreases(activity)ALOX12
C006680
CTDincreases(expression)BAX
C006680
CTDdecreases(expression)CCNA2
C006680
CTDdecreases(expression)CCND1
C006680
CTDincreases(expression)CCND1
C006680
CTDdecreases(expression)CCND1
C006680
CTDdecreases(reaction)CCND1
C006680
CTDdecreases(reaction)CCND1
C006680
CTDincreases(expression)CDK4
C006680
CTDincreases(activity)CFTR
C006680
CTDdecreases(expression)CSF2
C006680
CTDdecreases(reaction)CYP1A1
C006680
CTDincreases(expression)CYP1A1
C006680
CTDdecreases(reaction)CYP1A1
C006680
CTDincreases(expression)CYP1A1
C006680
CTDdecreases(activity)CYP1A1
C006680
CTDdecreases(expression)CYP1A1
C006680
CTDincreases(expression)CYP1A1
C006680
CTDincreases(chemical synthesis)CYP1A1
C006680
CTDincreases(metabolic processing)CYP1A1
C006680
CTDdecreases(activity)CYP1A2
C006680
CTDincreases(chemical synthesis)CYP1A2
C006680
CTDincreases(metabolic processing)CYP1A2
C006680
CTDaffects(binding)CYP1B1
C006680
CTDdecreases(activity)CYP1B1
C006680
CTDdecreases(reaction)CYP1B1
C006680
CTDincreases(expression)CYP1B1
C006680
CTDdecreases(activity)CYP1B1
C006680
CTDincreases(chemical synthesis)CYP1B1
C006680
CTDincreases(metabolic processing)CYP1B1
C006680
CTDdecreases(reaction)CYP2C9
C006680
CTDincreases(hydroxylation)CYP2C9
C006680
CTDdecreases(activity)CYP3A4
C006680
CTDdecreases(phosphorylation)GSK3B
C006680
CTDincreases(expression)HES1
C006680
CTDdecreases(reaction)HES1
C006680
CTDincreases(expression)HEY1
C006680
CTDdecreases(reaction)HEY1
C006680
CTDincreases(expression)HEY2
C006680
CTDdecreases(reaction)HEY2
C006680
CTDdecreases(reaction)HSD11B2
C006680
CTDincreases(activity)HSD11B2
C006680
CTDincreases(reaction)INS
C006680
CTDincreases(secretion)INS
C006680
CTDdecreases(activity)MAPK1
C006680
CTDdecreases(phosphorylation)MAPK1
C006680
CTDdecreases(activity)MAPK3
C006680
CTDdecreases(phosphorylation)MAPK3
C006680
CTDdecreases(activity)MAPK8
C006680
CTDdecreases(phosphorylation)MAPK8
C006680
CTDdecreases(activity)MMP2
C006680
CTDdecreases(reaction)MMP9
C006680
CTDincreases(activity)MMP9
C006680
CTDdecreases(activity)MMP9
C006680
CTDdecreases(expression)NAT1
C006680
CTDdecreases(localization)NFKB1
C006680
CTDdecreases(phosphorylation)NFKBIB
C006680
CTDincreases(activity)NOTCH1
C006680
CTDincreases(expression)NOTCH1
C006680
CTDdecreases(activity)PLAU
C006680
CTDdecreases(reaction)PMAIP1
C006680
CTDincreases(expression)PMAIP1
C006680
CTDdecreases(phosphorylation)PRKCA
C006680
CTDdecreases(reaction)PTGS2
C006680
CTDincreases(expression)PTGS2
C006680
CTDaffects(reaction)RB1
C006680
CTDdecreases(phosphorylation)RB1
C006680
CTDdecreases(reaction)RB1
C006680
CTDdecreases(localization)RELA
C006680
CTDincreases(expression)TP53
C006680
CTDincreases(metabolic processing)UGT2B15
C006680
CTDdecreases(expression)VEGFA
C006680
PubChem NoneuMABL1-GI(Protien) :
PubChem NoneuMAKR1C4-GI(Protien) :
PubChem PotencyuM14.989ALDH1A1-GI(Protien) :
PubChem PotencyuM1.995ALOX15-GI(Protien) :
PubChem PotencyuM15.849BLM-GI(Protien) :
PubChem NoneuMCASP6-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem PotencyuM5.012CYP2C19-GI(Protien) :
PubChem PotencyuM5.012CYP2C9-GI(Protien) :
PubChem PotencyuM31.623CYP2D6-GI(Protien) :
PubChem PotencyuM31.623CYP3A4-GI(Protien) :
PubChem NoneuMCYP3A4-GI(Protien) :
PubChem PotencyuM17.783FEN1-GI(Protien) :
PubChem PotencyuM35.481FEN1-GI(Protien) :
PubChem NoneuMGAPDH-GI(Protien) :
PubChem PotencyuM3.162HPGD-GI(Protien) :
PubChem PotencyuM7.943HPGD-GI(Protien) :
PubChem PotencyuM28.184HPGD-GI(Protien) :
PubChem NoneuMHPGD-GI(Protien) :
PubChem PotencyuM15.849L3MBTL1-GI(Protien) :
PubChem PotencyuM7.943MAPT-GI(Protien) :
PubChem PotencyuM10.000MAPT-GI(Protien) :
PubChem PotencyuM25.119MAPT-GI(Protien) :
PubChem PotencyuM28.184MAPT-GI(Protien) :
PubChem NoneuMMAPT-GI(Protien) :
PubChem NoneuMNR0B1-GI(Protien) :
PubChem NoneuMNR0B1-GI(Protien) :
PubChem NoneuMNR5A1-GI(Protien) :
PubChem NoneuMPLA2G7-GI(Protien) :
PubChem NoneuMPLA2G7-GI(Protien) :
PubChem PotencyuM3.162POLH-GI(Protien) :
PubChem PotencyuM15.101POLH-GI(Protien) :
PubChem PotencyuM1.413POLK-GI(Protien) :
PubChem PotencyuM1.778POLK-GI(Protien) :
PubChem PotencyuM2.239POLK-GI(Protien) :
PubChem PotencyuM19.953POLK-GI(Protien) :
PubChem NoneuMPSIP1-GI(Protien) :
PubChem NoneuMPSIP1-GI(Protien) :
PubChem NoneuMRIN1-GI(Protien) :
PubChem NoneuMSMARCA2-GI(Protien) :
PubChem NoneuMSMARCA2-GI(Protien) :
PubChem PotencyuM11.886TDP1-GI(Protien) :
PubChem PotencyuM16.789TDP1-GI(Protien) :
PubChem PotencyuM29.855TDP1-GI(Protien) :
PubChem PotencyuM44.668THRB-GI(Protien) :
PubChem PotencyuM0.631TP53-GI(Protien) :
PubChem NoneuMTRA-GI(Protien) :
PubChem NoneuMTRA-GI(Protien) :
ChEMBLPotencynM14988.900ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM1995.300ALOX15
-Target : CHEMBL2903
ChEMBLActivity-ALOX15
-Target : CHEMBL2903
ChEMBLPotencynM631.000APEX1
-Target : CHEMBL5619
ChEMBLPotencynM15848.900BLM
-Target : CHEMBL1293237
ChEMBLAC50nM501.190CYP1A2
-Target : CHEMBL3356
ChEMBLPotencynM5011.900CYP2C19
-Target : CHEMBL3622
ChEMBLPotencynM5011.900CYP2C9
-Target : CHEMBL3397
ChEMBLPotencynM31622.800CYP2D6
-Target : CHEMBL289
ChEMBLPotencynM31622.800CYP3A4
-Target : CHEMBL340
ChEMBLAC50nM31622.800CYP3A4
-Target : CHEMBL340
ChEMBLInhibition-EGLN1
-Target : CHEMBL5697
ChEMBLActivity-EGLN1
-Target : CHEMBL5697
ChEMBLActivity-GPR35
-Target : CHEMBL1293267
ChEMBLInhibition-HIF1AN
-Target : CHEMBL5909
ChEMBLPotencynM3162.300HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM28183.800HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM7943.300HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM2511.900HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM3981.100HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM1995.300HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM12589.300KDM4E
-Target : CHEMBL1293226
ChEMBLPotencynM891.300KDM4E
-Target : CHEMBL1293226
ChEMBLPotencynM7079.500KDM4E
-Target : CHEMBL1293226
ChEMBLPotencynM15848.900L3MBTL1
-Target : CHEMBL1287622
ChEMBLPotencynM7943.300MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM28183.800MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM25118.900MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM10000.000MAPT
-Target : CHEMBL1293224
ChEMBLActivity-MGAM
-Target : CHEMBL2074
ChEMBLActivity-NR3C1
-Target : CHEMBL2034
ChEMBLPotencynM5011.900RECQL
-Target : CHEMBL1293236
ChEMBLPotencynM28183.800RECQL
-Target : CHEMBL1293236
ChEMBLPotencynM15848.900RECQL
-Target : CHEMBL1293236
ChEMBLPotencynM44668.400THRB
-Target : CHEMBL1947
ChEMBLPotencynM631.000TP53
-Target : CHEMBL4096
Download gene sets gmt, text, Detailed text
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).