Tan Lab | DSigDB

Gene Set: D4 : CTD - 2-anthramine

Collection

D4 : CTD

Chemical Name

2-anthramine ( From PubChem : 2-AMINOANTHRACENE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
193.244 g/mol	1	1	4.1564	True

Structure

InChI

InChI=1S/C14H11N/c15-14-6-5-12-7-10-3-1-2-4-11(10)8-13(12)9-14/h1-9H,15H2

InChIKey

Links

Gene (10 / 19)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			AR		C006593
CTD	increases(activity)			AR		C006593
CTD	increases(activity)			CYB5A		C006593
CTD	increases(reaction)			CYB5A		C006593
CTD	increases(activity)			CYP1A2		C006593
CTD	increases(reaction)			CYP1A2		C006593
CTD	affects(metabolic processing)			CYP1A2		C006593
CTD	increases(activity)			HIF1A		C006593
PubChem	Potency-Replicate_1	uM	8.635	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	17.903	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	44.026	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	62.189	AHR	-	GI(Protien) :
PubChem	Potency	uM	1.995	ALDH1A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	9.856	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	24.337	ESR1	-	GI(Protien) :
PubChem	Potency	uM	2.371	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NFKBIA	-	GI(Protien) :
ChEMBL	Potency	nM	1995.300	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159

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