Tan Lab | DSigDB

Gene Set: D4 : CTD - 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one

Collection

D4 : CTD

Chemical Name

5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one ( From PubChem : OROXYLIN A )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
284.263 g/mol	2	5	2.8798	True

Structure

InChI

InChI=1S/C16H12O5/c1-20-16-11(18)8-13-14(15(16)19)10(17)7-12(21-13)9-5-3-2-4-6-9/h2-8,18-19H,1H3

InChIKey

Links

Gene (15 / 27)

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Source	Type	Gene	Other
CTD	decreases(expression)	ABCB1	C080669
CTD	decreases(activity)	ABCB1	C080669
CTD	decreases(reaction)	ABCB1	C080669
CTD	decreases(expression)	BCL2	C080669
CTD	decreases(expression)	CASP3	C080669
CTD	increases(cleavage)	CASP8	C080669
CTD	decreases(expression)	CASP9	C080669
CTD	increases(expression)	CHEK2	C080669
CTD	decreases(reaction)	CHEK2	C080669
CTD	decreases(expression)	FOS	C080669
CTD	decreases(reaction)	MAPK1	C080669
CTD	increases(phosphorylation)	MAPK1	C080669
CTD	decreases(phosphorylation)	MAPK1	C080669
CTD	decreases(reaction)	MAPK3	C080669
CTD	increases(phosphorylation)	MAPK3	C080669
CTD	decreases(phosphorylation)	MAPK3	C080669
CTD	decreases(expression)	MMP2	C080669
CTD	decreases(reaction)	MMP9	C080669
CTD	increases(activity)	MMP9	C080669
CTD	increases(expression)	MMP9	C080669
CTD	decreases(expression)	MMP9	C080669
CTD	increases(degradation)	PARP1	C080669
CTD	affects(localization)	PRKCD	C080669
CTD	decreases(reaction)	PRKCD	C080669
CTD	increases(expression)	TIMP2	C080669
CTD	increases(expression)	TP53	C080669
CTD	decreases(reaction)	TP53	C080669

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